Medical negligence claims alleging 'failure to diagnose' are a common cause of claims against general practitioners. In these claims there is often an underlying weakness in the GP's test result and patient tracking systems. This article discusses the duty of care of a GP to follow up patients and their test results. Guidance is provided on how to establish an effective test result tracking sys...

Interferon production and apoptosis in virus-infected cells are necessary to prevent progeny virus production and to eliminate infected cells. Paramyxovirus infection induces apoptosis through interferon regulatory factor 3 (IRF-3), but the exact mechanism of how IRF-3 functions is unknown. We show that IRF-3 is involved in the transcriptional induction of TRAIL, a key player in the apoptosis p...

Interferons (IFNs) have been used to treat mucosal lesions caused by human papillomavirus (HPV) infection, such as intraepithelial precursor lesions to cancer of the uterine cervix, genital warts or recurrent respiratory papillomatosis, to potentially reduce or eliminate replicating HPV plasmid genomes. Mucosal HPVs have evolved mechanisms that impede IFN-beta synthesis and downregulate genes i...

transluminal balloon valvuloplasty is an alternative to surgical valvotomy for congenital pulmonary valve stenosis. the aim of this study was to evaluate the long term results (to 13.5 years) of balloon pulmonary valvuloplasty. from june 1998 to january 2012, percutaneous balloon pulmonary valvuloplasty for congenital pulmonary valve stenosis was performed in 98 patients (50 males, 48 females, ...

introduction: differentiated thyroid carcinoma (dtc) is associated with excellent prognosis and high survival rates. this study was conducted to evaluate the influence of baseline and treatment-related factors on the health related quality of life (qol) in cured dtc. methods:this study was an analytic cross-sectional study on radio-iodine (rai) treated dtc patients during 2011-2012. the data on...

intervention in early childhood development as one of the social determinants of health, is important for reducing social gap and inequity. in spite of increasingly developing intensive neonatal care wards and decreasing neonatal mortality rate, there is no follow up program in iran. this study was carreid out to design high risk infants follow up care program with the practical aim of creating...

conclusions to enhance the follow-up rate, three strategies were proposed: patient-focused strategies such as emphasizing patient education upon discharge and providing rewards; structural-focused strategies such as scheduling home visits and uploading questionnaires onto the research center’s website; and provider-focused strategies such as selecting coordinators with good communication skills...

current mainstay of treatment for human immunodeficiency virus (hiv)-infected patients is highly active antiretroviral therapy (haart) but little is known about the long-term clinical outcome for hiv-infected patients who have received haart. determining factors associated with longterm survival in the course of treatment may allow modification to be made for patients who are at a greater risk ...

When thinking about traditional Iranian architecture, one imagines extensive ornamental patterns that adorn almost every surface of mosques and other prominent buildings. Yet, many theories of architecture since the beginning of twentieth century have considered ornamentation a superficial and superfluous layer. But, are these ornamental surfaces superficial and can they be removed so easily? T...