Ethanol-induced fat accumulation, the earliest and most common response of the liver to ethanol exposure, may be involved in the pathogenesis of liver diseases. Isoliquiritigenin (ISL), an important constituent of Glycyrrhizae Radix, is a chalcone derivative that exhibits antioxidant, anti-inflammatory, and phytoestrogenic activities. However, the effect of ISL treatment on lipid accumulation i...

Implicit statistical learning (ISL) is exclusive to neither a particular sensory modality nor a single domain of processing. Even so, differences in perceptual processing may substantially affect learning across modalities. In three experiments, statistically equivalent auditory and visual familiarizations were presented under different timing conditions that either facilitated or disrupted tem...

Islet-1 (ISL-1), a LIM-homeodomain transcription factor, has been recently found to be essential for promoting postnatal pancreatic islet proliferation. However, the detailed mechanism has not yet been elucidated. In the present study, we investigated the mechanism by which ISL-1 promotes β-cell proliferation through regulation of CyclinD1 in HIT-T15 and NIT-1 cells, as well in rat islet mass. ...

In this work we present a proof-theoretical justification for the intersection type assignment system (IT) by means of the logical system Intersection Synchronous Logic (ISL). ISL builds classes of equivalent deductions of the implicative and conjunctive fragment of the intuitionistic logic (NJ). ISL results from decomposing intuitionistic conjunction into two connectives: a synchronous conjunc...

A novel load balancing routing scheme is proposed for Polar-orbit Low Earth Orbit satellite networks. This scheme employs mobile agents to gather related routing information by migrating autonomously. And, stationary agents estimate Inter-satellite Link (ISL) cost, routing path cost and update routing items on satellites. In the proposed scheme, ISL queueing delay is estimated using M/M/1 queue...

Indian Sign Language (ISL) interpretation is the major research work going on to aid Indian deaf and dumb people. Considering the limitation of glove/sensor based approach, vision based approach was considered for ISL interpretation system. Among different human modalities, hand is the primarily used modality to any sign language interpretation system so, hand gesture was used for recognition o...

The global navigation satellite system (GNSS) is developing rapidly, and the related market applications scientific research are increasing. Studies based on large low Earth orbit (LEO) constellations have become hotspots. coverage of LEO constellation can reduce dependence satellites ground-monitoring stations improve precise determination (POD) accuracy satellites. In this paper, we simulate ...

Joint injuries during sporting activities might be reduced by understanding the extent of the dynamic motion of joints prone to injury during maneuvers performed in the field. Because instrumented spatial linkages (ISLs) have been widely used to measure joint motion, it would be useful to extend the functionality of an ISL to measure joint motion in a dynamic environment. The objectives of the ...

Objectives: Parents may have their infant sleep with them in the same bed (bed sharing [BS]), in the same room, but a separate bed (room sharing [RS]), or a separate room in a separate bed (solitary sleeping [SS]); prevalence estimates of these choices are limited. Little is known regarding the effects of infant sleep location (ISL) on infant or maternal sleep or other health outcomes. Methods:...

Abstract Background BRII-732, a prodrug of islatravir (ISL), is potent HIV-1 nucleotide reverse transcriptase translocation inhibitor. Following oral absorption, BRII-732 rapidly converted to ISL, which metabolized intracellularly the active metabolite, ISL triphosphate (ISL-TP). Single doses as low 0.5 mg significantly suppressed RNA by more than 1.0 log at day 7 in treatment-naive adults with...