background: identify the optimal technique of radiotherapy for patients with high grade glioma. our initial year of experience with rapidarc radiation therapy. materials and methods: planning ct scans of 50 patients with grade iv glioma were reviewed and three plan sets by 3d conformal radiotherapy (3dcrt), intensity modulated radiotherapy (imrt) and rapid arc (ra) were generated and the plans ...

Nasopharyngeal carcinoma (NPC) is highly radiosensitive, and radiotherapy recommended for newly diagnosed NPC. Because of the poor visual surgical field, narrow operating space, difficulty protecting internal carotid artery (ICA) wound healing, development NPC surgery has been severely limited. For recurrent NPC, some open approaches, such as maxillary swing, successfully solve above major prob...

The term of brachytherapy, also known as “internal radiotherapy, sealed source radiotherapy, curietherapy or endocurietherapy” is from Greek work brachy means short distance and therapy (treatment) and also known as internal radiotherapy or sealed source radiotherapy. Brachytherapy is a special form of radiotherapy where a radioactive source is carefully placed on or inside the area to be treat...

Hepatocellular carcinoma (HCC) is the second leading cause of cancer related death with increasing incidence. The standard treatments of HCC consist of surgical resection, liver transplantation, radiofrequency ablation and transarterial chemoembolization. However, because a large proportion of HCC patients are diagnosed in advanced stage, long-term prognosis is disappointing with few available ...

The emergence of vascular disrupting agents (VDAs) is a significant advance in the treatment of solid tumors. VDAs induce rapid and selective shutdown of tumor blood flow resulting in massive necrosis. However, a viable marginal tumor rim always remains after VDA treatment and is a major cause of recurrence. In this review, we discuss the mechanisms involved in the resistance of solid tumors to...

Dural metastasis from primary gastric adenocarcinoma has been rarely reported, and its prognosis is very poor because it frequently leads to acute subdural hematoma. Here, we describe a case with sequential spinal and cranial dural metastases from gastric adenocarcinoma without subdural hematoma. A 43-year-old woman with gastric adenocarcinoma and well-controlled peritoneal carcinomatosis prese...