The mammalian immune system constitutively senses vast quantities of commensal bacteria and their products through pattern recognition receptors, yet excessive immune reactivity is prevented under homeostasis. The intestinal microbiome can influence host susceptibility to extra-intestinal autoimmune disorders. Here we report that polysaccharide A (PSA), a symbiosis factor for the human intestin...

Gastrointestinal involvement in patients with systemic lupus erythematosus (SLE) is very diverse, and the frequency of occurrence and location along the digestive tract varies widely. Inflammatory processes secondary to immune complex deposits or vascular events may cause this involvement. One of the most characteristic gastrointestinal manifestations in these patients is the intestinal pseudo-...

BACKGROUND Intestinal intussusception is a common pathology among children, whereas it is a rare entity in adults. The child/adult ratio is abdominal surgeries and in 1/100 patients operated on for intestinal obstruction. Clinical manifestations of adult intussusception are nonspecific and patients may present with acute, intermittent or chronic symptoms, predominantly those of intestinal obstr...

In recent years, injuries induced by explosive blast have got more and more attention owing to weapon development and frequent terrorist activities. Tear, bleeding and edema of tissues and organs are the main manifestations of blast shock wave damage. Vascular endothelial barrier is the main defense of tissues and organs' integrity. This article aims to discuss possible mechanisms of endothelia...

Introduction Pseudoxanthoma elasticum (PXE) is a rare heritable disorder of the connective tissue. Up to 1964, approximately 400 cases had been reported (Suerig and Siefert, 1964). The lesion involves mainly the skin, the eyes and the cardiovascular system, giving rise to diverse clinical manifestations. Most of the reports have highlighted the association of cutaneous changes with angioid stre...

Phaeochromocytomas are rare neuroendocrine tumours with variable clinical signs and symptoms. Hypertension, tachycardia, sweating and headaches are cardinal manifestations. Although nausea and abdominal pain are the more common gastrointestinal features, rare gastrointestinal spectrums have been reported that can mimic abdominal emergencies. Metabolic effects of hypercatecholaminaemia are vast ...

Toxic effects associated with phenylbutazone therapy such as oedema, various types of skin rashes, agranulocytosis, thrombocytopenia, haemorrhagic manifestations and gastro-intestinal disorders are well known. Oedema was considered to be solely due to sodium retention and of little significance until Bruck et al. (I954) first suggested that a toxic effect on the kidney was induced by the drug, ...

Helicobacter pylori (H. pylori) are one of the most common bacterial infections, seen in humans, worldwide and their possible relationships to different diseases are a focus of attention nowadays. H. pylori may cause some extra intestinal manifestations some of which are dermatological conditions, including Henoch-Schönlein purpura (HSP), chronic urticaria and atopic dermatitis. We describe a 4...

Autosomal dominant polycystic kidney disease is a common hereditary disorder characterized by renal and extrarenal, cystic and noncystic manifestations. Connective tissue defects, including cerebral aneurysm, meningeal diverticula, abdominal wall hernias, intestinal diverticula, and cardiac valvular abnormalities, are widely known manifestations. Instead intracardiac aneurysms have never been r...

Many complications were reported secondary to herniation, including strangulation and incarceration, leading intestinal obstruction related clinical manifestations. Treating such cases is largely dependent on appropriately diagnosing evaluating them enhance the prognosis prevent a recurrence. In present literature review, we have discussed incarcerated hernias' radiological features. Physical e...