This study describes the existence and the clinical and electrophysiological features of multi-focal cortical dysplasia in epilepsy patients. Five patients with intractable focal epilepsy are reported. All patients underwent invasive presurgical video-electroencephalography monitoring. Localization of dysplastic areas was based on high-resolution magnetic resonance scanning, surface and intracr...

Synchronization of oscillatory EEG signals across different frequency bands is receiving waxing interest in cognitive neuroscience and neurophysiology, and cross-frequency coupling is being increasingly linked to cognitive and perceptual processes. Several methods exist to examine cross-frequency coupling, although each has its limitations, typically by being flexible only over time or over fre...

Statistical analysis techniques for highly complex structured data such as fMRI data should be thoroughly validated. In this process, knowing the ground truth is essential. Unfortunately, establishing the ground truth of fMRI data is only possible with highly invasive procedures (i.e. intracranial EEG). Therefore, generating the data artificially is often the only viable solution. However, ther...

Neural representations of specific stimuli rely on activity patterns in distributed neural assemblies [1-4]. According to one influential view, these assemblies are characterized by synchronized gamma-band activity (GBA) [5-11] that reflects stimulus-specific representations [12-14]. However, recent studies have shown that GBA is closely correlated with the overall amount of cellular activity a...

BACKGROUND Seizure prediction can increase independence and allow preventative treatment for patients with epilepsy. We present a proof-of-concept for a seizure prediction system that is accurate, fully automated, patient-specific, and tunable to an individual's needs. METHODS Intracranial electroencephalography (iEEG) data of ten patients obtained from a seizure advisory system were analyzed...

Complex neurophysiological examination (rheoencephalography, electroencephalography) was carried out in 12 adolescents 12 to 18 years old in order to reveal the peculiarities of cerebral structures functioning in adolescents with achondroplasia. Some deviations from the normal values were found out: reduced blood filling of the brain vessels in the pools of a. carotis interna and a. vertebralis...

* Corresponding Author: Wael Khreisat, P.O .box 211133, Amman 11121, Jordan. Phone office: 00962-6-5804804-66411 E-mail: [email protected] Introduction: To obtain a baseline for clinical application of Electroencephalography in children and to evaluate the Electroencephalography findings in children with various acute and chronic CNS disorders and non epileptic events. Methods: electroenc...

The recent surge in computational power has led to extensive methodological developments and advanced signal processing techniques that play a pivotal role in neuroscience. In particular, the field of brain signal analysis has witnessed a strong trend towards multidimensional analysis of large data sets, for example, single-trial time-frequency analysis of high spatiotemporal resolution recordi...

The distinction between memory for events and memory for facts rests on a range of findings indicating that different memory systems respectively subserve episodic and semantic memory functions. Whereas general knowledge clearly affects memory for events, the respective roles of encoding and retrieval processes in this interaction remain unclear. Using intracranial electroencephalography and mu...