Background: To evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhCG) before embryo transfer (ET). Materials and Methods: In this randomized placebocontrolled clinical trial, a total number of 182 infertile patients undergoing their first in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) were randomly assigned to receive 250 μg i...

Recent advances in epigenetics have made a tremendous impact on our knowledge of biological phenomena and the environmental stressors on complex diseases. Understanding the mechanism of epigenetic reprogramming during the occurrence of pulmonary hypertension (PH) is important for advanced studies and clinical therapy. In this article, we review the discovery of novel epigenetic mechanisms assoc...

Background: Cerebral Palsy can be defined as a cluster of disorders acting on person’s movement, posture, and balance. Palsy, which affects 2 to 3 out every 1000 live births, is caused by variety factors, including brain injury affect It’s linked the perinatal period in about 92% cases. Premature birth, infections, intrauterine growth restrictions, multiple gestations, other risk factors are al...

Pelvic actinomycosis is an uncommon, slowly progressing granulomatous infection that has been associated with the presence of intrauterine devices. Due to its unspecific clinical and radiologic findings, it can mimic pelvic or intra-abdominal malignancy leading to mutilating surgery of high morbidity. Rarely, diagnosis is made preoperatively and in most cases surgical intervention is necessary....

In mammals, the intrauterine condition has an important role in the development of fetal physiological systems in later life. Suboptimal maternal environment can alter the regulatory pathways that determine the normal development of the fetus in utero, which in post-natal life may render the individual more susceptible to cardiovascular or metabolic adult-life diseases. Changes in the intrauter...

background: intrauterine insemination (iui) is one of the most appropriate and cost-effective methods in infertility treatment. objective: we aimed to investigate effect of vaginal misoprostol on pregnancy rate after iui. materials and methods: two hundred and ten infertile women who were referred to infertility clinic of alzahra hospital by an indication of iui during 2012-2013 were randomly a...

oligohydramnios is frequently used to identify at risk fetuses. the purpose of this study was to assess adverse perinatal outcomes in oligohydramnios. subjects comprised pregnant women diagnosed either with (590) or without (597) oligohydramnios who delivered after hospital admittance from 2000 to 2010 . data, including the resuscitation of newborn, apgar score at 5 min, nicu admission, death i...

in mammals, the intrauterine condition has an important role in the development of fetal physiological systems in later life. suboptimal maternal environment can alter the regulatory pathways that determine the normal development of the fetus in utero, which in post-natal life may render the individual more susceptible to cardiovascular or metabolic adult-life diseases. changes in the intrauter...

BACKGROUND Mirror syndrome (MS) is a rare obstetric condition usually defined as the development of maternal edema in association with fetal hydrops. The pathogenesis of MS remains unclear and may be misdiagnosed as pre-eclampsia. CASE PRESENTATION We report a case series of MS in which fetal therapy (intrauterine blood transfusion and pleuroamniotic shunt) resulted in fetal as well as matern...

By the end of 2014, a total of 955,081 persons in the United States (299.5 per 100,000 population) had received a diagnosis of human immunodeficiency virus type 1 (HIV-1) infection (1). The annual estimated number of HIV infections and incidence rate in the United States decreased from 2010 to 2014, and the survival rate has increased over time (1). Effective highly active antiretroviral therap...