We investigated a non-invasive measurement for changes in finger blood flow during wakefulness and sleep. Changes in finger blood flow, reflected by pulse wave amplitude (PWA) derived from finger plethysmography, were compared with changes in forearm vascular flow assessed by venous occlusion plethysmography after intra-arterial infusion of norepinephrine (NE), phentolamine, and isoproterenol (...

The sophistication of bedside intensive care unit (ICU) monitoring equipment and the precision of its displayed values may tempt clinicians to accept these data without question. However, critically ill patients place substantial demands on these measurement technologies. Although the technology is governed by rigorous industry standards, it is not foolproof. To ensure accuracy and recognize an...

Abstract After decades of research on non-invasive glucose monitoring, invasive devices based finger blood sampling are still the predominant reference for diabetic patients accurately measuring levels. Meanwhile, continues improving point-of-care technology toward development painless and more accurate devices. Raman spectroscopy is well-known as a potentially valuable approach However, previo...

This review paper describes innovative methods and technology for non-invasive human brain physiological monitoring based on measuring the acoustic properties of the brain parenchyma. The clinical investigation of new technology shows the similarity between the invasively recorded intracranial pressure (ICP) and non-invasively recorded intracranial blood volume (IBV) pulse waves, slow waves and...

In perioperative medicine, hemodynamic management aims at an optimization of perfusion pressure and oxygen delivery in order to maintain or restore adequate cellular metabolism (1). To optimize cardiopulmonary function, hemodynamic management triggers the administration of fluids and vasoactive agents according to predefined target values of hemodynamic variables. This is often referred to as “...

INTRODUCTION Invasive arterial blood pressure monitoring is a common practice in intensive care units (ICUs). Accuracy of invasive blood pressure monitoring is crucial in evaluating the cardiocirculatory system and adjusting drug therapy for hemodynamic support. However, the best site for catheter insertion is controversial. Lack of definitive information in critically ill patients makes it dif...

The prognostic value of central systolic blood pressure has been established recently. At present, its noninvasive assessment is limited by the need of dedicated equipment and trained operators. Moreover, ambulatory and home blood pressure monitoring of central pressures are not feasible. An algorithm enabling conventional automated oscillometric blood pressure monitors to assess central systol...

The prognostic value of central systolic blood pressure has been established recently. At present, its noninvasive assessment is limited by the need of dedicated equipment and trained operators. Moreover, ambulatory and home blood pressure monitoring of central pressures are not feasible. An algorithm enabling conventional automated oscillometric blood pressure monitors to assess central systol...