Two simple and accurate methods are described for the determination of piroxicam and tenoxicam in their pharmaceutical preparations. The spectrophotometric method involves the oxidation of these drugs with potassium iodate in acid medium with the liberation of iodine and subsequent extraction with cyclohexane followed by measuring the absorbance at lambda=522 nm. Beer's law is obeyed in the con...

Reactive oxidants damage the retinal pigment epithelium (RPE), which is required for viability of overlying photoreceptors. Smoking which leads to chronic accumulation of reactive oxidants in the circulation is linked to age-related macular degeneration (AMD) where RPE death is seen along with photoreceptor loss in the central macular region of the retina. It is unclear why this damage is conce...

Membrane potential and current were studied in cut end fibres of frog skeletal muscle under current and voltage clamp conditions, by the double sucrose gap technique. Similar action potentials were recorded under current clamp conditions with either the microelectrode or the double sucrose gap techniques. Under voltage clamp conditions, the control of the membrane potential was maintained adequ...

129I is a major by-product of nuclear fission that is of concern because of its extremely long half-life (~16 million yrs), perceived toxicity through bioaccumulation, and the increasing inventory of this radionuclide worldwide. Relatively high concentrations of iodate (27.3%) and organoiodine (23.9%) are present in a 129I-conatminated aquifer at the Savannah River Site (SRS), SC, U.S.A. To det...