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The title mol-ecule, C(12)H(9)NO(2), adopts a trans configuration about the olefinic double bond. The dihedral angle between the naphthalene ring system (r.m.s. deviation = 0.012 Å) and the nitro-ethenyl group (r.m.s. deviation = 0.032 Å) is 12.66 (5)°. The mol-ecules are linked into a two-dimensional network parallel to the bc plane by C-H⋯O hydrogen bonds. The substituted benzene rings in adj...
In the title Schiff base, C(15)H(15)NO, the benzene rings form a dihedral angle of 74.91 (1)°. There is a strong intra-molecular O-H⋯N hydrogen bond.
In the title compound, C(10)H(13)N(3)O(3), the 3,4-dimeth-oxy-benzyl-idene and hydrazinecarboxamide groups are oriented at a dihedral angle of 53.82 (6)° and an intra-molecular N-H⋯N hydrogen bond generates an S(5) ring motif. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into sheets propagating in (-201), which feature R(1) (2)(5), R(2) (2)(8) and R(2) (4)(14) loops.
The title compound, C(9)H(11)N(3)O, was synthesized by the reaction of 4-methyl-benzaldehyde with semicarbazide. The mol-ecule adopts an E configuration about the central C=N double bond and the dihedral angle between the mean planes of the benzene ring and the carboxamide groups is 17.05 (9)°. The hydrazine N atoms are twisted slightly out of the plane of the carboxamide group [C-C-N-N torsion...
The selectivity of the ubiquitin–26 S proteasome system (UPS) for a particular substrate protein relies on the interaction between a ubiquitin-conjugating enzyme (E2, of which a cell contains relatively few) and a ubiquitin–protein ligase (E3, of which there are possibly hundreds). Post-translational modifications of the protein substrate, such as phosphorylation or hydroxylation, are often req...
In the title compound, C(16)H(12)N(2)O, the dihedral angle between the two aromatic ring systems is 68.54 (5)°. The mol-ecular packing is stabilized by intra- and inter-molecular O-H⋯N and intra-molecular C-H⋯N hydrogen-bond inter-actions.
In the title compound, C(12)H(10)N(2)O(2), the dihedral angle between the benzene and furan rings is 52.54 (7)°. In the crystal, inter-molecular N-H⋯O hydrogen bonds and C-H⋯π inter-actions link the mol-ecules.
The concept that E2 deficiency is involved in MCT-PH may be correct; but this concept may be incorrect in human PAH. Monocrotaline is a toxin that, in male rats, reduces plasma testosterone levels by 50%, and gonadal toxicity could be the reason for reduced E2 levels. Furthermore, in the YUAN et al. [1] study, animals were not synchronised for oestrous cycle, and this may also have contributed ...
At the DAΦNE-II workshop a session was devoted to the prospects of measuring the hadronic cross section at the new DAΦNE. The session included six papers, two theoretical and four experimental ones. The theory treatises, one on the muon anomaly and the other on measuring the hadronic cross section using initial state radiation at e + e − colliders, set the background for the four experimental d...
The title compound, C17H20O2, has an E conformation about the bridging C=C bond. The cyclo-hexene ring adopts an envelope conformation with the dimethyl-substituted C atom as the flap. Its mean plane makes a dihedral angle of 7.20 (12)° with the benzene ring. In the crystal, neighbouring mol-ecules are connected via C-H⋯O hydrogen bonds, forming chains running along the a-axis direction.
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