نتایج جستجو برای: iridoids
تعداد نتایج: 297 فیلتر نتایج به سال:
Plants and their active constituents play an important role in the prevention of a variety of ailments. Most of the species of the Genus Vitex are used therapeutically in ancient Indian systems of medicine especially, Ayurveda and Siddha. The genus Vitex contains about 270 species distributed around the world. These species contain a variety of potentially bioactive molecules, such as iridoids,...
Extracts of seven medicinal plants used specifically against cutaneous leishmaniasis in the Madre de Dios region of Peru were evaluated in vitro against promastigote and axenic amastigote forms of Leishmania amazonensis. One of them showed interesting leishmanicidal activities (IC(50)=5 microg/ml in amastigotes). Bio-guided isolation of the stem bark's ethanol extract of Himatanthus sucuuba (Sp...
A new iridoid, pedunculariside, together with the known iridoid agnuside were isolated from the butanol extract of Vitex peduncularis stem bark. Both pedunculariside and agnuside showed preferential inhibition of COX-2, with IC50 values of 0.15 +/- 0.21 mg/ml and 0.026 +/- 0.015 mg/ml respectively, while having only small inhibitory effects on COX-1. Both compounds did not exhibit cytotoxicity ...
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