We have developed a highly sensitive, two-site immunoradiometric assay (IRMA) for human parathyrin (PTH) that is specific for the intact, secreted, biologically active 84-amino-acid peptide. This assay has several technical advantages: it does not detect even high concentrations of inactive carboxyl-terminal fragments, results are available within 24 h, and the detection limit for intact hormon...

Medical images can be a valuable resource for reliable information to support medical diagnosis. However, the large volume of medical images makes it challenging to retrieve relevant information given a particular scenario. To solve this challenge, content-based image retrieval (CBIR) attempts to characterize images (or image regions) with invariant content information in order to facilitate im...

We report the development and characterization of an IRMA for the direct measurement of nicked human chorionic gonadotropin (hCGn) in blood and urine. hCGn derived from a reference preparation of hCG used as an immunogen elicits monoclonal antibodies (mAbs) with enhanced recognition of human luteinizing hormone epitopes. The most specific assay for pregnancy hCGn is an IRMA composed of one mAb ...

Yüzyıllar boyunca fikirlerin ve kültürlerin aktarımında önemli rol oynayan kitaplar; günümüzün dijitalleşen yapısı ile birlikte geçmiş, şimdi gelecek bağlantı kurma konusunda bir iletişim aracıdır. Kitabın bizlere ne anlattığının yanı sıra tasarımı da titiz araştırma, incelik özen isteyen alandır. Zaman içerisinde kitap teknolojik gelişmelerin ışığında farklılaşmış deneyselliğe daha açık hale g...

J. Russo , M.D. (*) • I. H. Russo , M.D. Irma H Russo MD Breast Cancer Research Laboratory, Fox Chase Cancer Center , Cottman Avenue 333 , Philadelphia , PA 19111 , USA e-mail: [email protected]; [email protected]

Abstract We have reconstructed integrated water vapor (IWV) using the zenith wet delays to track properties of hurricanes and explore their spatial temporal distributions estimated from 922 GPS stations. Our results show that a surge in GPS-derived IWV occurred at least six hours prior landfall two major (Harvey Irma) struck Gulf East Coasts USA 2017. observed enhanced IWV, particular, for loca...

Astronomical arrays operating at (sub)millimeter wavelengths are seriously compromised by rapid variations in atmospheric water vapor that distort the phase coherence of incoming celestial signals. The signal received by each antenna of the array suffers a phase delay that varies rapidly with time and from antenna to antenna. Unless corrected, these distortions limit the coherence time of the a...

We evaluated cathepsin D concentrations in 318 breast carcinoma specimens with a standardized IRMA and established distribution values of 5.9-217.8 nmol/g (median 51.8). Concentrations of cathepsin D did not correlate with age or with concentrations of HER-2/neu oncoprotein, estrogen receptor, or epidermal growth factor receptors. A significant correlation was observed between cathepsin D and p...

This paper describes the results of the information modelling work group from the International Workshop on Models For Computer-Integrated Construction in Finland, October 1992. At this workshop, researchers from around the world presented their individual modelling efforts. These models’ parallel goals and abundant similarities led the participants to combine their individual results into a si...

Osteocalcin or bone gamma-carboxyglutamic acid (gla) protein and Bone-specific alkaline phosphatase (b-AP) total protein levels were evaluated as indicators of bone turnover in twenty patients with sickle cell haemoglobinopathies and in twenty normal healthy individuals. The serum bone-specific alkaline phosphatase total protein level was measured by immunoradiometric (IRMA) method. The concent...