Introduction: Depression is a mood disorder in which feelings of sadness, loss, anger, or frustration interfere with everyday life for one to several weeks. Several studies have shown that iron nanoparticles have neuroprotective and anti-inflammatory effects. This study aimed to evaluate anti-depressive effect of iron nanoparticles in male rats.  Methods: Depression was induced by Lipopol...

Irradiation of a toluene solution containing cyclopentadienone tricarbonyl iron complexes and isocyanides with blue LEDs afforded the formation isolation 12 triisocyanide complexes, two which, namely tris(2,6-dimethylphenyl isocyanide)(η 4 -tetraphenylcyclopenatedienone)iron, [Fe(C 9 H N) 3 (C 29 20 O)], tris(naphthalen-2-yl -tetraphenylcyclopenatedienone)iron acetone hemisolvate, 11 7 O)] 2 ·C...

iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. iron is absorbed by the duodenum and requires an acidic environment for optimal absorption. iron is found for 70% in erythrocytes, and 30% in storage, and a small amount in myoglobin and cytochromes. iron supplementation reduces anemia in breastfed infants and increases in significant dose...

Carbon monoxide-releasing molecules (CO-RMs) are compounds capable of delivering controlled amounts of CO within a cellular environment. Ruthenium-based carbonyls [tricarbonyldichloro ruthenium(II) dimer and tricarbonylchloro-(glycinato)ruthenium(II)] and boronacorbonates (sodium boranocarbonate) have been shown to promote vasodilatory, cardioprotective, and anti-inflammatory activities in a va...

Redox-inactive metal ions that function as Lewis acids play pivotal roles in modulating reactivities of oxygen-containing metal complexes in a variety of biological and biomimetic reactions, including dioxygen activation/formation and functionalization of organic substrates. Mononuclear nonheme iron(III)-peroxo species are invoked as active oxygen intermediates in the catalytic cycles of dioxyg...

The two potentially tridentate and monoprotic Schiff bases acetylpyridine benzoylhydrazone (HL(1)) and acetylpyridine 4-tert-butylbenzoylhydrazone (HL(2)) demonstrate remarkable coordination versatility towards iron on account of their propensity to undergo tautomeric transformations as imposed by the metal centre. Each of the pyridyl aroylhydrazone ligands complexes with the ferrous or ferric ...

Accumulating evidence suggests that ezetimibe may be a promising agent for treatment of nonalcoholic fatty liver disease and steatohepatitis (NAFLD/NASH). Phlebotomy and dietary iron restriction reduce serum transaminase in NAFLD/NASH patients. Recent studies have shown that a mutual effect exists between lipid metabolism and iron metabolism. Accordingly, we examined the effect of ezetimibe on ...