BACKGROUND In the last two years several cases of severe contact dermatitis related to newly acquired sofas and armchairs originating from China have been published. The responsible allergen is dimethylfumarate (DMF), an extremely potent sensitizer and irritant found in sachets inside the furniture. Recently, cases of contact dermatitis related to shoes and riding helmets have also been describ...

Irritant contact dermatitis (ICD) is a condition caused by chemicals that damage skin structures in direct non-allergic way. Dermatologic findings may present broad spectrum due to frequency and route of exposure individual susceptibility. The most critical point the diagnosis treatment ICD determine irritant since its cessation best treatment. Specifically, geriatric patients, questioning abou...

Contact dermatitis is one of the most common occupational diseases, with serious impact on quality of life, lost days at work and a condition that may be chronically relapsing. Regular prophylactic skin cream application is widely acknowledged to be an effective prevention strategy against occupational contact dermatitis; however, compliance rates remain low. To present a simple programme for s...

OBJECTIVE To investigate the outcome of unclassified eczema (UE). Eczema refers to a set of highly heterogeneous clinical conditions including contact dermatitis (CD) and several types of endogenous eczema. In clinics, however, the eczema of a large proportion of patients does not fit any known patterns and has been diagnosed as unclassified eczema. The prognosis of UE is largely unknown. DES...

E Szél, H Polyánka, K Szabó, P Hartmann, D Degovics, B Balázs, IB Németh, C Korponyai, E Csányi, J Kaszaki, S Dikstein, K Nagy, L Kemény, G Erős Department of Dermatology and Allergology, University of Szeged MTA SZTE Dermatological Research Group Institute of Surgical Research, University of Szeged Department of Pharmaceutical Technology, University of Szeged Unit of Cell Pharmacology, Hebrew ...

Leg amputees who can't use prostheses and patients with arthritis are often dependent on crutches. Their chronic use can exert significant friction forces. The palmar skin will respond by forming a hyperkeratotic callus. We report for the first time unilateral palmar callus formation caused by friction from using crutches. Another possible adverse effect is the triggering of irritant contact de...

The function of the intraepithelial lymphocyte (IEL) network of T cell receptor (TCR) gammadelta(+) (Vgamma5(+)) dendritic epidermal T cells (DETC) was evaluated by examining several mouse strains genetically deficient in gammadelta T cells (delta(-/-) mice), and in delta(-/-) mice reconstituted with DETC or with different gammadelta cell subpopulations. NOD.delta(-/-) and FVB.delta(-/-) mice s...

Patch testing is a well-established method of diagnosing contact allergy wherein patients with a history and clinical picture of contact dermatitis are re-exposed to the suspected allergens under controlled conditions to verify the diagnosis [1]. The results of first innovative patch-testing technique were presented by the German dermatologist, Josef Jadassohn (1863-1936) in 1895. The safety an...

The preservative methyldibromo glutaronitrilc (MDBGN) is used non-occupationally and occupationally. High contact allergy rates have been reported when tested in consecutive dermatitis patients as well as clinical cases with allergic contact dermatitis. Up till now there has been no agreement on which patch test preparation to use to trace contact allergy to MDBGN. From the year 2005 on, MDBGN ...