The inhibition of corrosion of mild steel in hydrochloric acid by isatin glycine (ING) and isatin (IN) at 30-60 o C and concentrations of 0.0001 M to 0.0005 M was studied via weight loss method. At the highest inhibitor concentration studied ING exhibited inhibition efficiency of 87% while IN exhibited 84% at 60 o C. A chemical adsorption mechanism was proposed on the basis of the temperature e...

A number of N-arylmethyl substituted indole derivatives have been synthesized and their effectiveness against ADP and arachidonic acid induced platelet aggregation in human plasma was determined. The desired compounds were synthesized by reacting the appropriate aniline derivative with isatin (or substituted isatin) to form the corresponding imine structures. The so formed compound was then act...

Some new isatin3hydrazone derivatives that are Isatin3(benzylidene)hydrazone, Isatin3-(methyl ethylide)hydrazone, isatin 3-(isoproplylidene)hydrazone have been synthesized from the reaction of isatin3-hydrazone and different aldehydes and ketones. Thestructure of synthesized compound is assigned on the basis of, IR, 1HNMR, 13CNMRdata. The anti microbial activity was done by disk diffusion metho...

the interaction between isatin-β-thiosemicarbazone (ibt) and calf thymus dna (ct-dna) was investigated in physiological buffer (ph 7.4) using neutral red (nr) dye as a spectral probe by uv–vis absorption and fluorescence spectroscopy, as well as viscosity measurements. the ibt is stabilized by intercalation in the dna ( k [ibt –dna] =1.03×105 m−1), and displaces the nr dye from the nr–dna comple...

THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(trifluoro-meth-oxy)-1H-indole-2,3-dione], C9H4F3NO3, crystallized with two mol-ecules in the asymmetric unit. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules to form layers parallel to the ab plane. In addition, π-π stacking inter-actions are observed with a centroid-centroid distance of 3.721 (1) Å. The near planarity of the two isatin ring syst...

Isatin is a heterocyclic nitrogen compound that has attracted much interest in recent years due to its diverse biological and pharmacological activities. It can be used many medical applications, such as antidiabetic, antibiotic, anticancer agents. The isatin molecule also prepared from different substrates by various methods, the methods of Sandmeyer, Stolle, Gassman, Meanwell Hewawasam others...

Schiff bases of isatin with aminothiazole, its N-mannich bases and Spiro isatin derivatives were synthesized. Their chemical structures were confirmed by Infrared, 1H-Nuclear Magnetic Resonance data and elemental analysis. Antimicrobial evaluation was performed by the agar diffusion method against four pathogenic bacteria and two pathogenic fungi. Anti-inflammatory activity was tested by carrag...

The effects of the composition and rheology of the fermentation medium on the antibiotic production by Streptomyces hygroscopicus CH-7 were studied. To increase the yields of hexaene H-85 and elaiophylin, the basic fermentation medium was reformulated using different carbon (glucose, lactose, ribose, fructose and trehalose) and nitrogen (isatin-Schiff bases) sources. The maximum yields of hexae...