نتایج جستجو برای: ischemic brain edema

تعداد نتایج: 578948  

Journal: :Acta neurochirurgica. Supplement 2006
E M Nemoto

Traumatic brain injury and stroke are both characterized by an ischemic core surrounded by a penumbra of low to hyperemic flows. The underperfused ischemic core is the focus of edema development, but the source of the edema fluid is not known. We hypothesized that flow of edema fluid into the tissue is derived from cerebral venous circulation pressure, which always exceeds intracranial pressure...

Journal: :Neurocritical care 2014
W Taylor Kimberly Thomas W K Battey Ly Pham Ona Wu Albert J Yoo Karen L Furie Aneesh B Singhal Jordan J Elm Barney J Stern Kevin N Sheth

BACKGROUND Brain edema is a serious complication of ischemic stroke that can lead to secondary neurological deterioration and death. Glyburide is reported to prevent brain swelling in preclinical rodent models of ischemic stroke through inhibition of a non-selective channel composed of sulfonylurea receptor 1 and transient receptor potential cation channel subfamily M member 4. However, the rel...

Journal: :iranian journal of basic medical sciences 0
iraj aghaei department of neuroscience, guilan trauma research center, poursina hospital, guilan university of medical sciences, rasht, iran babak bakhshayesh department of neurology, poursina hospital, guilan university of medical sciences, rasht, iran hamed ramezani department of neurology, poursina hospital, guilan university of medical sciences, rasht, iran mahmood moosazadeh health sciences research center, school of health, mazandaran university of medical sciences, sari, iran mohammad shabani neuroscience research center, neuropharmacology institute, kerman university of medical sciences, kerman, iran

objective(s): preclinical studies show that iron plays a key role in mediating neuronal injury. this study was performedin order to identify the relationship between the serum level of ferritin and severity of the brain injury which occur after an intracerebral hemorrhage (ich). materials and methods:this was a cross sectional descriptive – analytic study, which was conducted on those patients ...

Background & Aims: Decompressive Craniectomy (DC) is recommended for patients with extensive cerebral infarction. At this study, we aimed to assess the mortality and 3-month outcome of these patients who are not going under DC. Material & Methods: In this prospective descriptive study, all patients referred to Imam Reza Hospital in Urmia, Iran, from 2017-2019 with extensive ischemic stroke wit...

2017
Nabi Shamsaei Soheila Erfani Masoud Fereidoni Ali Shahbazi

INTRODUCTION Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage. Evidence indicates that exercise reduces the ischemia and reperfusion-induced brain damages in animal models of stroke. In the present study, the effect of exercise preconditioning on brain edema and neurological movement disorders following...

2017
Nannan Yu Zhenguo Wang Yucen Chen Juntao Yang Xuan Lu Yi Guo Zelin Chen Zhifang Xu

BACKGROUND Cerebral edema, erupting simultaneously with severe ischemic stroke, might lead to increased intracranial pressure, cerebral herniation, and ultimately death. Studies conducted previously by our team have demonstrated the fact that bloodletting puncture at hand twelve Jing-well points (HTWP) could alleviate cerebral edema, which mainly results from the disruption of blood-brain barri...

Journal: :Journal of Cerebral Blood Flow & Metabolism 2017

Journal: :Stroke 2009
Wenlan Liu Jill Hendren Xu-Jun Qin Ke Jian Liu

BACKGROUND AND PURPOSE A major limitation of tissue plasminogen activator (tPA) thrombolysis for ischemic stroke is the narrow time window for safe and effective therapy. Delayed tPA thrombolysis increases the risk of cerebral hemorrhage and mortality, which, in part, is related to neurovascular proteolysis mediated by matrix metalloproteinases (MMPs). We recently showed that normobaric hyperox...

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