Pellagra is an exceptional skin involvement in celiac disease. Ischemic cardiomyopathy is another rare event in celiac disease. Its pathogenesis remains not yet elucidated. We report a case of a 34year old patient of presenting with pellagra and cardiomyopathy revealing a celiac disease.

In patients with myotonic dystrophy (MD), impairment of the conduction system is a common and progressive finding. However, only a few cases of MD with cardiomyopathy have been reported. Herein we report a case of MD with progressive non-ischemic cardiomyopathy and severe electrocardiographic abnormalities.

Ischemic stroke temporally related to cocaine abuse has become increasingly common in young adults. Despite this relation, however, the pathogenesis of infarction in many of these patients remains obscure. I report the case of a 39-year-old man who developed occlusion of the frontopolar branches of the left middle cerebral artery 1 hour after intravenous cocaine use. Eleven days later he develo...

There is an increasing number of patients with mitral regurgitation secondary to dilated cardiomyopathy. Recent data suggest that mitral regurgitation (MR) can be surgically corrected in heart failure with symptomatic improvements and favourable reverse left ventricular remodeling. However, several questions remain to be answered, regarding the optimal management of functional mitral regurgitat...

Nearly 30% of ischemic strokes have an unknown cause, which are referred to as cryptogenic (CS). Imaging studies suggest that a large proportion these patients show features consistent with embolism, and thus the term embolic stroke undetermined source (ESUS) was proposed describe CS patients. Atrial cardiomyopathy predisposes thrombus formation even in absence atrial fibrillation (AF). This ma...

Many diabetic patients suffer from cardiomyopathy, even in the absence of vascular disease. This diabetic cardiomyopathy predisposes patients to heart failure and mortality from myocardial infarction. Evidence from animal models suggests that reactive oxygen species play an important role in the development of diabetic cardiomyopathy. Our laboratory previously developed a transgenic mouse model...