BACKGROUND Stroke and mortality risk among heart failure patients previously diagnosed with different manifestations of vascular disease is poorly described. We conducted an observational study to evaluate the stroke and mortality risk among heart failure patients without diagnosed atrial fibrillation and with peripheral artery disease (PAD) or prior myocardial infarction (MI). METHODS Popula...

conclusions: left ventricular systolic heart failure, may result in inter and intra-atrial asynchrony even in clinically stable patients without significant pulmonary hypertension and diastolic dysfunction. results: in heart failure patients either inter or intra-atrial asynchrony were far more common in comparison with normal subjects (p=0.008 and p=0.007 respectively). patients and methods: t...

PURPOSE OF REVIEW The aim of this review was to discuss recent advances in clinical aspects of stem cell therapy in heart failure with emphasis on patient selection, stem cell types and delivery methods. RECENT FINDINGS Several stem cell types have been considered for the treatment of patients with heart failure. In nonischemic heart failure, transplantation of CD34 cells improved myocardial ...

AIMS The aims of the study were to study the demographical and clinicopathological characteristics of patients presenting with heart failure and evaluate the 1 year outcomes and to identify risk predictors if any. METHODS AND RESULTS A prospective observational study was conducted in consecutive patients of systolic heart failure. The study was divided into two parts-an initial 6 month enrolm...

Cardiovascular disease (CVD) encompasses several diseases: atherosclerotic CVD (including coronary heart disease [CHD], peripheral arterial disease [PAD], and ischemic stroke), hemorrhagic stroke, congestive heart failure, hypertension, rheumatic heart disease, and congenital heart defects. This article will focus on reviewing the evidence relating periodontal disease and CVD arising from ather...

Metabolic therapy represents an innovative approach to the treatment of coronary artery disease and heart failure. The metabolic modulator, trimetazidine (Vastarel MR), offers particular positive effects in reducing the cell loss and reorganization that characterize the process of left ventricle remodeling, and is useful in improving ischemic or failed cell metabolism. Correction of the metabol...

BACKGROUND The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is an important measurement instrument for assessing the quality of life of heart failure patients. Despite being largely used within our context, the questionnaire had not yet been translated and validated into the Portuguese language. OBJECTIVE Of this study was to translate and validate the Portuguese version of the M...

Few data exist on the pathophysiologic changes in pediatric heart failure. Most of the knowledge has evolved from animal models of ischemic or idiopathic dilated cardiomyopathy. This review addresses the pathophysiologic changes that occur in the failing heart from animal models and the adult experience to unique aspects of heart failure in children.