ARID domain proteins are members of a highly conserved family involved in chromatin remodeling and cell-fate determination. Dril1 is the founding member of the ARID family and is involved in developmental processes in both Drosophila and Caenorhabditis elegans. We describe the first embryological characterization of this gene in chordates. Dril1 mRNA expression is spatiotemporally regulated and...

Serotonin (5-HT) is a neuromodulator that plays many different roles in adult and embryonic life. Among the 5-HT receptors, 5-HT2B is one of the key mediators of 5-HT functions during development. We used Xenopus laevis as a model system to further investigate the role of 5-HT2B in embryogenesis, focusing on craniofacial development. By means of gene gain- and loss-of-function approaches and ti...

The factors governing the pattern formation process in the early morphogenesis of a marine colonial hydroid, Dynamena pumila, have been studied. Two different types of morphogenesis have been distinguished. Morphogenesis of the first type goes on via changes in cell shape and cell axis orientation, while morphogenesis of the second type is based upon the active coordinated cell movements associ...

Candida albicans is a major fungal pathogen of humans, accounting for 15% nosocomial infections with an estimated attributable mortality 47%. C. usually benign member the human microbiome in healthy people. Under constant exposure to highly dynamic environmental cues diverse host niches, has successfully evolved adapt both commensal and pathogenic lifestyles. The ability undergo reversible morp...

Branching morphogenesis is the developmental program responsible for generating a large surface to volume ratio in many secretory and absorptive organs. To accomplish branching morphogenesis, spatiotemporal regulation of specific cell subpopulations is required. Here, we review recent studies that define the contributions of distinct cell subpopulations to specific cellular processes during bra...

The work demonstrates the influence of undifferentiated connective tissue dysplasia on male reproductive function, shows which dysplastic-dependent pathology genital area affects spermogram indices in men. Shown are local problems deep pathophysiological and histological prerequisites their development factor infertility a married couple. paper importance principles joint related specialists at...

UNLABELLED The coordinated mechanisms balancing promotion and suppression of dendritic morphogenesis are crucial for the development of the cerebral cortex. Although previous studies have revealed important transcription factors that promote dendritic morphogenesis during development, those that suppress dendritic morphogenesis are still largely unknown. Here we found that the expression levels...

aim: abnormal joint mobility is an important factor in movement dysfunction and physical disability. a general lack of descriptive details exists for measurements of hip rotation range of motion (rom). this study was designed to establish the influence of hip position on active and passive range of motion of the hip in external and internal rotation(ext & int rot). material & methods: ...

in this research, the influence of bolt preload on the fatigue strength of 2024-t3 aluminium alloy double lap bolted joints has been studied experimentally and numerically. to do so, three sets of the specimens were prepared and each of them subjected to tightening torque of 1,2.5 and 5 n-m and then fatigue tests were conducted under various cyclic axial load levels. in the numerical method, th...

abstract   background: sacroiliac joint (sij) dysfunction is a widely known but poorly defined   cause of low back pain. to our knowledge, few published studies have been   conducted to evaluate systematically the prevalence and significance of concomitant   sacroiliac joint dysfunction in patients with herniated lumbar discs. as concomitant   sij dysfunction in low back pain patients is likely...