Differentiation of gammadelta and alphabeta T cells from a common precursor cell depends on productive rearrangement and expression of TCRgammadelta or TCRbeta genes, but whether it is an instructive or a stochastic mechanism that is responsible for this process is unclear. We report that expression of the productively rearranged TCRgamma transgene competitively inhibits alphabeta thymocyte dev...

Production of type I interferon (IFN; IFN-alphabeta) increases host susceptibility to Listeria monocytogenes, whereas type II IFN (IFN-gamma) activates macrophages to resist infection. We show that these opposing immunological effects of IFN-alphabeta and IFN-gamma occur because of cross talk between the respective signaling pathways. We found that cultured macrophages infected with L. monocyto...

The development of pre-T cells with productive TCR-beta rearrangements can be mediated by each the pre-T cell receptor (pre-TCR), the TCR-alphabeta as well as the TCR-gammadelta, albeit by distinct mechanisms. Although the TCR-gammadelta affects CD4-8- precursor cells irrespective of their rearrangement status by TCR-beta mechanisms not involving TCR-beta selection, both the pre-TCR and the TCR...

The main purpose of this paper is to prove the following result. Let X be a real or complex Banach space, let L(X) be the algebra of all bounded linear operators on X, let A(X) ⊆ L(X) be a standard operator algebra, and let T : A(X) → L(X) be an additive mapping satisfying the relation T (A2n+1) = 2n+1 ∑ i=1 (−1)i+1Ai−1T (A)A2n+1−i, for all A ∈ A(X) and some fixed integer n ≥ 1. In this case T ...

Abstract We provide a proof of Jacobson’s theorem on derivations primitive rings with nonzero socle. Both and its formulation (in terms the so-called differential operators left vector spaces over division ring) underlie our paper. apply to describe standard operator real, complex, or quaternionic normed spaces. Indeed, when space is infinite-dimensional, every derivation such ring form $$A\rig...

We study the ground-state properties of hard-core bosons trapped by arbitrary confining potentials on one-dimensional optical lattices. A recently developed exact approach based on the Jordan-Wigner transformation is used. We analyze the large distance behavior of the one-particle density matrix, the momentum distribution function, and the lowest natural orbitals. In addition, the low-density l...

Let N be a near ring. An additive mapping f : N → N is said to be a right generalized (resp., left generalized) derivation with associated derivation d onN if f(xy) = f(x)y + xd(y) (resp., f(xy) = d(x)y + xf(y)) for all x, y ∈ N. A mapping f : N → N is said to be a generalized derivation with associated derivation d onN iff is both a right generalized and a left generalized derivation with asso...