BACKGROUND Macrophage activation syndrome (MAS) is a severe, potentially life-threatening condition induced by chronic rheumatic diseases, especially systemic-onset juvenile idiopathic arthritis (SoJIA) in childhood. This study aimed to analyze the clinical and laboratory characteristics of systemic-onset juvenile idiopathic arthritis (SoJIA) with macrophage activation syndrome (MAS) in 13 pati...

Introduction Familial Mediterranean Fever (FMF) as an ethnic disease is wide-spread in Armenia. In most cases FMF manifests in childhood. Joint involvement is the third major FMF manifestation. It usually presents as acute recurrent arthritis (ARA), arthralgia, more rare chronic arthritis (Juvenile Idiopathic Arthritis, JIA), which are important to better learn more about the overlap between th...

Introduction Systemic Juvenile Idiopathic Arthritis (sJIA) is a disease with systemic inflammatory features as well as arthritis. Before biologic agents were available, a significant proportion of affected children suffered from poor outcomes. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry is a rich resource of information about pediatric rheumatic diseases includin...

OBJECTIVE To determine the clinical and biochemical characteristics of children with Juvenile Idiopathic Arthritis (JIA) at a tertiary care centre in Karachi, Pakistan. STUDY DESIGN A descriptive study. PLACE AND DURATION OF STUDY Paediatric Rheumatology Clinic of The Aga Khan University Hospital (AKUH), Karachi, from January 2008 to December 2011. METHODOLOGY Clinical and laboratory prof...

Received: Oct 02, 2012 Accepted: Nov 04, 2012 Ann Paediatr Rheum 2012; 1:231-236 DOI: 10.5455/apr.110420121342 Introduction Juvenile idiopathic arthritis ( JIA), consisting of heterogeneous clinical features, is the most common rheumatologic disease in children [1]. Onset of the disease is observed before the age of 16. 10% of patients suffer chronic anterior uveitis which is a major cause of v...

Recent recognition of the markedly high prevalence of temporomandibular joint (TMJ) arthritis in children with juvenile idiopathic arthritis (JIA) coupled with the significant morbidity associated with TMJ damage has prompted increased interest in both the clinical and pathological aspects of TMJ arthritis. This review focuses on the prevalence of TMJ arthritis in JIA, the imaging modalities us...