Kala-azar or visceral leishmaniasis is usually associated with progressive emaciation in spite of the fact that the patients generally have a good, at times voracious, appetite and their diet is not often greatly restricted. Apart from emaciation, signs of avitaminosis, viz, xerophthalmia, Bitot's spots, glossitis, angular stomatitis, dryness of the skin, etc., have often been noticed by one of...

During the session of the Congress of the Far Eastern Association of Tropical Medicine held at Calcutta in December 1927, Lieut.-Co . B. N. Chopra of the Calcutta School of Tropical Medicine demonstrated a simple te> 01 diagnosing kala-azar. With a view to find on its efficiency 1 undertook to carry out som* control tests in a non-kala-azar distric ? part of this work was commenced in April 192...

Serologic parameters of kala-azar were evaluated by Western blot analysis. Sera from kala-azar patients with confirmed diagnoses were screened for immunoglobulin G (IgG) and IgG subclass-specific reactivity against Leishmania donovani membrane antigen (LAg). Heterogeneous LAg-specific IgG reactivity with numerous proteins with molecular masses ranging from 18 to 190 kDa was observed. Though the...

The incidence of infantile visceral leishmaniasis is currently increasing, at least in the Mediterranean region. Most cases seen in France occur on the Mediterranean coast or are imported from Africa. However, contamination in other regions of France is not an exceptional occurrence and may raise diagnostic problems. The parasite reservoir is the dog population in which the prevalence of Leishm...

had several private cases sent to us by private practitioners of the city. Almost all those cases were in the initial stages. The peripheral blood of these patients was examined every week (each time about ̂ dozen slides), but I rarely found the parasites in the early stages. Still, other changes in the blood and the characteristic temperature of the disease made us suspect a case to be one of K...

remain unknown. S. delphini has rarely been identified in horses, but, as we observed, it may be misidentified by conventional methods. Although colonization or contamination appeared most likely in the instances we describe, these findings suggest that this opportunistic pathogen can be found in horses and might be pathogenic in certain situations. Our findings highlight the importance of usin...

A pentavalent antimony compound (Sdt. 561, solustibosan, antimony-v-hexonate, containing 20 mg. of antimony per c.cm. of solution) , that made a stable solution and could be given intramuscularly, was first introduced b) Prof. H. Schmidt, the pioneer worker on pent*1' valent antimony compounds. Kikuth and Schmidt (1938) found that this compound possessed a marked curative action in the le*,' ma...