Kinematics in osteoarthritic knees may be impeding efforts to reproduce "normal" knee kinematics in the prosthetic knee. Fourteen subjects with unilateral symptomatic knee osteoarthritis performed a supine leg press from 0 degrees to 90 degrees flexion against a 150-N load. The tibiofemoral contact pattern was recorded for both knees using sagittal T1-weighted magnetic resonance imaging. Severi...

Patients: 146 patients ≥ 45 years of age (mean age 62 y, 61% women) with symptomatic knee OA (American College of Rheumatology criteria: long-term knee pain and ≥ 1 osteophyte on knee radiograph [equivalent to Kellgren-Lawrence grade 2]), mild or worse weight-bearing pain (Western Ontario and McMaster Universities [WOMAC] pain subscale), and pain or discomfort referable to the knee joint. Exclu...

We have measured the dynamic movement of the lumbar spine in 57 patients with degenerative lumbar disc disease. Each completed a questionnaire which recorded pain and subjective signs and symptoms. From plain lateral radiographs, the subjects were graded using the criteria of Kellgren and Lawrence and those of Lane et al, which are both based on the severity of degenerative changes. Measurement...

BACKGROUND The influence of pre-existing radiographic osteoarthritis on the functional outcome of elderly patientents with displaced intracapsular fractures of the femoral neck treated by hemiarthroplasty is unclear. METHODS We prospectively examined the impact of pre-existing osteoarthritis on the functional outcome of 126 elderly patients with displaced intracapsular fracture of the femoral...

The purpose of this study was to investigate whether platelet-rich plasma therapy for early knee osteoarthritis is associated with good clinical outcomes and a change in magnetic resonance imaging (MRI) structural appearances. The design was a prospective cohort study following patients 1 year after platelet-rich plasma therapy for knee osteoarthritis. Twenty-two patients were treated with plat...

In population studies of a disease much valuable iniformation is lost if, through lack of uniformity of diagnostic criteria and survey techniques, the results of one study cannot be directly compared with another. Two conferences (Kellgren, Jeffrey, and Ball, 1963; Bennett and Burch, 1967) have suggested diagnostic criteria for ankylosing spondylitis and these are shown in Tables I and II. Both...

We report a study of 112 patients with primary anteromedial osteoarthritis of the knee and their families. Sibling risk was determined using randomly selected single siblings. Spouses were used as controls. The presence of symptomatic osteoarthritis was determined using an Oxford knee score of > or= 29 supported by a Kellgren and Lawrence radiological score of II or greater. Using Fisher's exac...

We aimed to explore the relationship between comorbidities and structural progression in symptomatic knee and/or hip osteoarthritis (OA) patients. analyzed 5-year outcome of non-obese participants (body mass index (BMI) < 30 kg/m2) from KHOALA cohort having OA (Kellgren Lawrence (KL) ≥ 2). The primary endpoint was radiological progression, defined as ΔKL 1 target joint at 5 years. secondary ...

All current studies of rheumatoid arthritis are hindered by the lack of a precise definition of the disease. Patients in an arthritis clinic are selected, so that those with mild or short-lived forms of the disease are probably rarely seen. Because of this, better definition of rheumatoid arthritis is being sought through epidemiological studies. Four approaches are available, either separately...