transmembrane envelope glycoproteins. Most of the exJoseph G. Sodroski Department of Cancer Immunology and AIDS posed surface of the assembled trimer is composed of Dana-Farber Cancer Institute elements of gp120, with the gp41 ectodomain largely Department of Pathology buried in the interior of the complex (Figure 1, left panel). Harvard Medical School and The gp120 glycoprotein binds the host ...

Johansen, K. 2017. Towards an evidence-based assessment of early motor performance in the child health services. Psychometric properties and clinical utility of the Structured Observation of Motor Performance in Infants. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1317. 95 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9861-0. The Swedish ...

The application of multi-object instruments to nearby galaxies permits the spectroscopy of large samples of faint stars. Such data are needed to determine the kinematics and metallicity distributions of stellar systems, to complement the excellent photometric data now becoming available. Together, these data should reveal the star formation and evolutionary histories of Local Group galaxies. Th...

Ethanol-induced damage is largely attributed to its toxic metabolite, acetaldehyde. Clearance of acetaldehyde is achieved by its oxidation, primarily catalyzed by the mitochondrial class II aldehyde dehydrogenase (ALDH2). ALDH1B1 is another mitochondrial A LDH t hat s hares 75% peptide sequence h omology w ith A LDH2. R ecent p opulation studies in C aucasians suggest a r ole f or ALDH1B1 in e ...

Visual, NIR, and H α surface photometry of the oval disk galaxy M 94 (NGC 4736) was performed to study the distribution of mass in old stars and the distribution of the warm emission line gas. The radial profile of the inner stellar disk is steeper than exponential and displays twisted and deformed isophotes. Dust is not responsible for these deviations. The investigation of a number of morphol...

We discuss the scale dependence of a skewed parton distribution of the pion obtained from a generalized light-cone wave function overlap formula. Using a simple ansatz for the transverse momentum dependence of the light-cone wave function and restricting ourselves to the case of a zero skewedness parameter the skewed parton distribution can be expressed through an ordinary parton distribution m...

Background: DNA damage is one of the major consequences of radia on exposure onto the biological systems. A series of compounds including flavanoids were found to render DNA protec on against radia on damage. In this study we elucidated the poten al of ru n and ru n hydrate to protect plasmid DNA against damage induced by irradia on. Materials and Methods: DPPH and hydroxyl radical scavenging a...

This paper is concerned with the problem of motion generation via cyclic variations in selected degrees of freedom (usually referred to as shape variables) in mechanical systems subject to nonholonomic constraints (here the classical one of a disk rolling without sliding on a at surface). In earlier work, we identiied an interesting class of such problems arising in the setting of Lie groups, a...

We present a spectroscopic survey of 2046 red giant stars, distributed over the central 4 kpc×2 kpc of the Small Magellanic Cloud (SMC). After fitting and removing a small velocity gradient across the SMC (7.9 km s −1 deg −1 oriented at 10 • E of N), we measure an rms velocity scatter of 27.5 ± 0.5 km s −1. The line of sight velocity distribution is well-characterized by a Gaussian and the velo...

Low-pressure capacitively-coupled discharges with an additional DC bias applied to a separate electrode are important for plasma-assisted etching for semiconductor device manufacturing. Measurements of the electron velocity distribution function (EVDF) impinging on the wafer and in the plasma bulk show complex structure of EVDF with multiple peaks and steps. These features in the electron energ...