Background Preeclampsia is a specific pregnancy syndrome. Early diagnosis and proper administration of preeclampsia can lead to improved maternal and neonatal outcome. We aimed to investigate the uterine artery Doppler ultrasound in predicting the preeclampsia in women with a high-risk pregnancy. Materials and Methods This analytic study was conducted on 160 primigravida women with gestational...

The updated Guidelines on Prevention of Perinatal Group B Streptococcal Disease, issued by the Centers for Disease Control and Prevention, actually represent the mainstay in the prevention of neonatal early-onset group B streptococcal (GBS) sepsis. According to these guidelines, patients with possible preterm delivery are screened for GBS colonization and offered intrapartum prophylaxis only if...

BACKGROUND The purpose of this research is to discover whether measurement of cervical length and cervical volume at term is helpful in predicting the onset of labor in VBAC candidates. METHODS Transvaginal sonographic evaluations of the cervixes of pregnant women who desired to undergo VBAC were performed between 36 - 40 weeks gestation. Clinical information such as labor onset time, gestati...

Objective: To analyse the onset of uterine contractions and preterm delivery in order to document any diurnal influence. Methodology: Hospital records of the patients admitted with the diagnosis of preterm labor were retrieved from January 2003 to February 2007 from Sobhraj Maternity Hospital, Karachi. Time of onset of uterine contractions establishment of preterm labor parity and gender of the...

BACKGROUND AND OBJECTIVE Oxytocin for labor augmentation is widely used in obstetric care in Western countries. Two recent, smaller studies found opposing results regarding the association between prenatal exposure to oxytocin for labor augmentation and attention-deficit/hyperactivity disorder (ADHD). In Denmark, oxytocin is the medication used for nearly all medical augmentations of labor, and...

The dramatic increase in uterine growth during late pregnancy and the generation of labor contractions require dynamic remodeling of myometrial smooth muscle-ECM interactions. In many tissues, such interactions are provided by focal adhesions; however, there are no data as to the expression of focal adhesion proteins or of focal adhesion signaling in the myometrium. In this study, we show that ...

OBJECTIVE To evaluate the effect of vaginal disinfection with chlorhexidine gel during labor on vertical transmission of group B streptococcus, as a method to prevent vertical transmission and subsequent neonatal early onset group B streptococcal disease. STUDY DESIGN A prospective study with randomization of 1020 parturients to one of three groups as soon as labor started. In all parturients...

There is evidence from many studies indicating that a number of specific quiescent and contractile associated proteins are temporally regulated in the myometrium during pregnancy. In this present investigation we provide data that strongly suggest that myometrial connexin-43, cyclooxygenase-1 and -2 (COX-1 and -2), and Gs alpha proteins are also spatially expressed within the human uterus durin...