the popularity of non-dairy probiotic products continues to persist as the consumers prefer functional foods satisfying their health needs. among these promising foods, probiotic grape drink would have beneficial effects on modifying gastrointestinal flora and human health. in this study, the pasteurized grape drink was inoculated by three species of lactic acid bacteria (lactobacillus delbruec...

BACKGROUND Bioplastics, like polylactic acid (PLA), are renewable alternatives for petroleum-based plastics. Lactic acid, the monomer of PLA, has traditionally been produced biotechnologically with bacteria. With genetic engineering, yeast have the potential to replace bacteria in biotechnological lactic acid production, with the benefits of being acid tolerant and having simple nutritional req...

This report attempts to frame the debate about clinical administration of sodium bicarbonate in the setting of lactic acidosis in terms of simple questions. Specifically, we address why we develop lactic acidosis in some circumstances, how acute lactic acidosis impairs cardiovascular function and why sodium bicarbonate may have deleterious effects which limit its utility. We also attempt to exp...

Biguanide poisoning is associated with lactic acidosis. The exact mechanism of biguanide-induced lactic acidosis is not well understood. In the previous issue of Critical Care, Protti and colleagues demonstrated that biguanide-induced lactic acidosis may be due in part to a reversible inhibition of mitochondrial respiration. Thus, in the absence of an antidote, increased drug elimination throug...

abstract       background and objective: probiotics are living microorganisms that have beneficial effects on the health of digestive system. the aim of this study was to evaluate the antimicrobial ability of acidic and neutral supernatants (culture supernatant) of lactic acid bacteria against common bacterial pathogens.        methods: four species of lactic acid bacteria (lactobacillus planta...

case presentation a 52-year-old malay gentleman, with hepatitis c virus and hiv infection was admitted to the intensive care unit for severe lactic acidosis, with concurrent escherichia coli bacteremia with multiorgan dysfunction. the patient was started on highly active antiretroviral therapy, which included tenofovir, 5 weeks before presentation. antimicrobial therapy, continuous veno-venous ...

The consideration of the manner in which various metabolites are removed from the living cell by the process of oxidation presents a problem which, if it is to be considered quantitatively, necessitates a detailed knowledge of the course of comparable reactions in vitro. I t is, therefore, desirable to consider such reactions from many points of view before attempting to analyze the more compli...