A 22-year-old male European brown bear (Ursus arctos arctos) was presented to the Onderstepoort Veterinary Academic Hospital after an acute onset of hind limb paralysis 4 days earlier. Previous radiographs revealed marked degenerative joint disease of the stifles, tarsi and digits. The clinical findings were consistent with acute disc prolapse. Lateral radiographs of the entire vertebral column...

A two-year-old male Pomeranian dog was presented to a veterinary hospital due the side effects of surgical correction for patellar luxation. Stifle joint arthrodesis (SJA) performed on patient’s right leg using autologous bone-grafting techniques. The femur and tibial were angled 120–130°, an SJA plate fixed front two bones. After performing fusion limb, medial-patellar-luxation-(MPL)-correctiv...

OBJECTIVE The redox enzyme p66Shc produces hydrogen peroxide and triggers proapoptotic signals. Genetic deletion of p66Shc prolongs life span and protects against oxidative stress. In the present study, we evaluated the role of p66Shc in an animal model of diabetic wound healing. RESEARCH DESIGN AND METHODS Skin wounds were created in wild-type (WT) and p66Shc(-/-) control and streptozotocin-...

1. The over-all and regional metabolism of non-esterified fatty acids (NEFA) was studied using a combination of isotopic and arteriovenous-difference techniques. 2. There was a common linear relationship, whether stearic, palmitic or oleic acids were used as tracer, between the arterial NEFA concentration and the rates of entry and oxidation. 3. Assuming that the tracer used reflected the metab...

BACKGROUND AND PURPOSE An animal spinal tumor model is needed to better simulate the clinical situation and to allow percutaneous puncture, which may provide an experimental platform for the new nonvascular interventional therapies. We established a rabbit spinal tumor model through a CT-guided percutaneous puncture inoculation technique for nonvascular interventional therapy. MATERIALS AND M...

The purpose of this study was to test the effect of high voltage stimulation (HVS) on blood flow velocity (BFV) in the rat hind limb. A 20-MHz pulsed Doppler device was used to measure BFV changes in the femoral artery of 20 anesthetized rats after electrical stimulation. The animals were stimulated under the following conditions: four different pulse rates, changes in stimulus voltage, and cha...

UNLABELLED The study of neuropathic pain has focused on changes within the nervous system, but little research has described systemic changes that may accompany neuropathic pain. OBJECTIVE As part of a larger project characterizing the metabolic, activity, and musculoskeletal changes associated with neuropathic pain, the objective of the current study was to characterize changes in spontaneou...

Strigiformes are an order of raptorial birds consisting exclusively of owls: the Tytonidae (barn owls) and the Strigidae (true owls), united by a suite of adaptations aiding a keen predatory lifestyle, including robust hind limb elements modified for grip strength. To assess variation in hind limb morphology, we analysed how the dimensions of the major hind limb elements in subfossil and modern...

the aim of this study was to find any structural differences between the digital pads of forelimbs and hind limbs as well as more careful investigation of the internal and external structures of the toe-pad. in this study, pad morphology and cytology in litoria caerulea is described using sem, tem and light microscopy. at the gross anatomical level, toe-pads in hind limbs were subdivided into m...