The superior colliculus (SC) is critical in localizing salient visual stimuli and making decisions on the location of the next saccade. Lateral interactions across the spatial map of the SC are hypothesized to help mediate these processes. Here, we investigate lateral interactions within the SC by applying whole-cell recordings in horizontal slices of mouse SC, which maintained the local struct...

Systemically-administered dopaminergic drugs have been found to facilitate sexual behavior of men and male rats. The present experiments investigated the localization within the brain of dopaminergic effects on copulation of male rats. Apomorphine, a dopamine agonist, was microinfused into the medial preoptic area, caudate-putamen, nucleus accumbens, lateral septum and lateral ventricle. The lo...

The effects of physosti~ine, nicotine and scopolamine were studied on the activity of single lateral geniculate neurons in the acute cat. Most of the lateral geniculate neurons selected were P-cells. These increased their responses to ipsilateral optic tract and midbrain reticular formation stimulation. Nicotine and physostigmine in doses of 25 pg/kg i.v. significantly increased the spontaneous...

SUMITOMO, I. Effects of Thalamic Midline Nuclei Stimulation upon Lateral Geniculate Transmission in Rats: Inhibition of Principal Cells and Excitation of Internuncial Cells. Tohoku J. exp. Med., 1974, 114 (3), 227-240Effects of low-frequency stimulation of thalamic midline nuclei .(MID) upon unitary activities of principal (P) and internuncial (I) cells of the lateral geniculate body were exami...

26 To investigate vestibulo-ocular reflex (VOR) adaptation produced by changes in 27 peripheral vestibular afference, we developed and tested a vestibular “prosthesis” that 28 senses yaw-axis angular head velocity and uses this information to modulate the rate of 29 electrical pulses applied to the lateral canal ampullary nerve. The ability of the brain to 30 adapt the different components of t...

To investigate vestibuloocular reflex (VOR) adaptation produced by changes in peripheral vestibular afference, we developed and tested a vestibular "prosthesis" that senses yaw-axis angular head velocity and uses this information to modulate the rate of electrical pulses applied to the lateral canal ampullary nerve. The ability of the brain to adapt the different components of the VOR (gain, ph...

Electrical stimulation of the horizontal limb of the diagonal band of Broca (HDB) was coupled with recording of evoked potentials in the piriform cortex. Stimulation of the HDB caused an enhancement of the late, disynaptic component of the evoked potential elicited by stimulation of the lateral olfactory tract but caused a suppression of the synaptic potential elicited by stimulation of the pos...

INTRODUCTION The purpose of this prospective, randomized single-blind study was to evaluate the degree of pulpal anesthesia obtained with frequency-dependent conduction blockade of the inferior alveolar nerve (IAN). METHODS Eighty adult volunteers randomly received two IAN blocks: an IAN block followed by continuous electrical stimulation for 3 minutes of the first molar or lateral incisor fo...

Episodic memory is critical to daily life functioning. This type of declarative memory declines with age and is the earliest cognitive function to be compromised in Alzheimer's disease (AD). Subjective memory complaints are commonly reported by older adults and have been considered a risk factor for developing AD. The possibilities for prevention of memory disorders in older adults have increas...

Stimulation of the skin evokes topographically organized activation in somatosensory cortex. This representation is context dependent, however, since a different cortical topography is observed in area 3b when stimulated with complex tactile stimuli that evoke the von Békésy funneling illusion. Here we report on the population responses, as observed with intrinsic optical imaging, of area 1 and...