This study investigated the potential anticaries properties of synthetic 1,4-naphthoquinone derivatives. Synthetic derivatives (2-4) were designed and synthesized by employing lawsone methyl ether (LME, 1), a plant-derived 1,4-naphthoquinone, as lead compound. The compounds characterized infrared spectroscopy, 1H-nuclear magnetic 13C- nuclear high-resolution mass spectrometry. Minimum inhibitor...

We report in vitro and in vivo anti-inflammatory activities of a series of copper(II)-lawsone complexes of the general composition [Cu(Law)2(LN)x(H2O)(2-x)]·yH2O; where HLaw = 2-hydroxy-1,4-naphthoquinone, x = 1 when LN = pyridine (1) and 2-aminopyridine (3) and x = 2 when LN = imidazole (2), 3-aminopyridine (4), 4-aminopyridine (5), 3-hydroxypyridine (6), and 3,5-dimethylpyrazole (7). The comp...

Streptomyces coelicolor Müller contains two superoxide dismutases (SODs), nickel-containing (NiSOD) and iron- and zinc-containing SOD (FeZnSOD). The sodF gene encoding FeZnSOD was isolated by using PCR primers corresponding to the N-terminal peptide sequence of the purified FeZnSOD and a C-terminal region conserved among known FeSODs and MnSODs. The deduced amino acid sequence exhibited highest...

Henna (Lawsonia inermis L.) is a commercial and export-oriented important perennial shrub used in the ornamentation of palm, feet, dyeing hair, etc. Developing high-yielding varieties elite plant materials are best method to increase productivity quality henna. An experiment was conducted at research farm ICAR-Central Arid Zone Research Institute, Regional Station, Pali-Marwar, Rajasthan during...