Background: Leishmania is an intracellular protozoan parasite that enters and reproduces in macrophage cells. Macrophages are important immune cells phagocyte many pathogens such as bacteria, fungi, parasites spp. but incapable of killing this parasite, living the phagosomes infected macrophages, multiplying, resulting divesting macrophages appearance lesions. Many present drugs for treatment h...

localized leishmania lymphadenitis (l.l.l) is a self limited clinical presentation of cutaneous leishmaniasis. microscopic findings in l.l.l are very similar to toxoplasma lymphasenitis. in all cases, an intensive microscopic search should be done for leishman bodies. in this study, we describe our microscopic findings and results of our immnohistochemical (ihc) study with a panel of monoclonal...

abstract          background and objective: cutaneous leishmaniasis is a parasitic disease and a health problem in different parts of iran, especially two cities of mashhad and chabahar. due to morphological similarities of most leishmania species and difference in reservoirs of l. major and l. tropica, it is necessary to determine the parasite specie to combat the disease. thus, this study use...

background: leishmaniasis has been identified as a major public health problem in tropical and sub-tropical countries. the present study was aimed to investigate antileishmanial effects of various extracts of berberis vulgaris also its active com-poenent, berberine against leishmania tropica and l. infantum species on in vitro ex-periments. methods : in this study in vitro antileishmanial activ...

b a ckground: cutaneous leishmaniasis due to leishmania major is a serious and increasing problem affecting manyrural areas of 17 out of 31 provinces in iran. little is known about sand fly fauna and leishmaniases in eastern iran and no study has been carried out in sarbisheh county. the aim of this study was to determine sand flies composi- tion and probable leishmania infection to find the pr...

Leishmania tropica is the causative agent of Old World anthroponotic cutaneous leishmaniasis, which is characterized by lesions that take an extended period of time to heal, often resulting in disfiguring scars, and are more refractory to treatment than leishmaniasis caused by Leishmania major. Immunologic studies involving experimental animal models of L. tropica infection are virtually nonexi...

Recently two hypotheses have been proposed for the evolution of Leishmania involving respectively a Neotropical or Paleartic origin for the species. Here an alternative proposal on the phylogeny of Leishmania based on the major divisions within the genus is presented. In this hypothesis a Neotropic origin is retained for L. (Viannia) and Paraleishmania, a recently described section within the g...

Materials and methods: Th e eff ects of HBO on Leishmania tropica promastigote and amastigote forms were studied at a pressure of 2.5 atmosphere absolute (ata). We examined the cytotoxic eff ect of HBO on promastigotes using the trypan blue exclusion test and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) dye-reduction assay. To investigate the eff ects of HBO treatment ...

Leishmaniasis is common in western and southern portions of Venezuela, where it tends to occur in hot, humid regions below 600 meters. This article describes the results of a survey pe$ormed during 1978-1979 in westem Venzzuela above 600 meters, where teishmaniasis caused by a recentb iaknt$ed parusitz (Leishmania gamhami) is common, but where the mucosal lesions often associated with the disea...