This paper characterises low-affinity antibiotic binding interactions by the T2 (CPMG) method. Three different compounds, a ketolide ‘telithromycin’ (HMR 3647), a macrolide ‘roxithromycin’ and a lincosamide ‘clindamycin’ belonging to the macrolide–lincosamide–streptogramin B (MLSB) class of antimicrobial agents were examined against Escherichia coli, Streptococcus pneumoniae and Staphylococcus ...

Abstract The aim of this study was to investigate the rate resistance macrolide-lincosamide-streptogramin B (MLSB) antibiotics, mechanisms underlying and evaluate their relationship with virulence genes profiles 435 Bulgarian clinical isolates Staphylococcus aureus . highest observed penicillin (96.09%), followed by erythromycin clindamycin (34.02 22.76%, respectively). Of tested strains S. , 9...

Antibiotic resistance genes (ARGs) pose a widespread concern for human health and wastewater treatment plants (WWTPs) are considered to be major source of ARG transmission. In this paper, the potential hosts genetic characteristics ARGs in influent, activated sludge effluent WWTPs Xinjiang were studied by metagenomics. Bacitracin gene (bacA), beta-lactamase (class A beta-lactamase), multidrug (...

The conversion of cattle manure into biogas in anaerobic digestion (AD) processes has been gaining attention recent years. However, antibiotic consumption continues to increase worldwide, which is why antimicrobial concentrations can be expected rise and digestate. This study examined the long-term synergistic effects antimicrobials on manure. prevalence resistance genes (ARGs) changes microbia...

Helicobacter pylori is a well-known pathogen involved in the development of peptic ulcer, gastric adenocarcinoma and other forms of gastric cancer. Recently, there has been more considerable interest in strain-specific genes located in plasticity regions with great genetic variability. However, little is known about many of these genes. Studies suggested that certain genes in this region may pl...