PURPOSE Age-related degradation of the elastic lamina in Bruch's membrane may have a permissive effect on the growth of choroidal neovascularization (CNV). This study investigated the influence of defective elastic fiber maintenance in the development of laser-induced CNV. METHODS A mouse lacking lysyl oxidase-like (LOXL)-1, an enzyme essential for elastin polymerization, was studied. The mor...

The purpose of this study was to gain more information on the structure of different layers of renal arteryand comparing these structures in post-natal male and female sheep. To do so, right and left renal arteries of6 adult and 6 newborn animals were dissected; the middle parts of arteries were only collected. After tissueprocessing using paraffin embedding method, 5–6-μm sections were cut and...

We have used a biomembrane force probe decorated with P-selectin to form point attachments with PSGL-1 receptors on a human neutrophil (PMN) in a calcium-containing medium and then to quantify the forces experienced by the attachment during retraction of the PMN at fixed speed. From first touch to final detachment, the typical force history exhibited the following sequence of events: i), an ini...

the purpose of this study was to gain more information on the structure of different layers of renal arteryand comparing these structures in post-natal male and female sheep. to do so, right and left renal arteries of6 adult and 6 newborn animals were dissected; the middle parts of arteries were only collected. after tissueprocessing using paraffin embedding method, 5–6-μm sections were cut and...

An analytical solution for nonlinear vibration of an initially stressed beam with elastic end restraints resting on a nonlinear elastic foundation is obtained. As a first step in solving nonlinear vibration equation, the linear vibration mode functions for a beam with elastic end restraints resting on a linear elastic foundation are obtained. Then, the nonlinear vibration equation is solved by ...

A PVC-based membrane containing cerium phosphate was developed. Unlike the cerium phosphate itself that acts as a cation exchanger, the membrane exhibited anion-exchange properties. Therefore, the utility of this compound as a sensory element for detection of molybdate ions was pursued. The response of molybdate selective electrode based on this membrane was perfectly linear in the concentr...

We investigate interactions between an elastic membrane and a substrate characterized by quenched positional disorder in the height function. We show that the positional disorder transforms the standard secondary DLVO minimum into two separate states: the hovering state characterized by a planar membrane at a finite separation from the interface and a pinned state where the membrane follows clo...