OBJECTIVE: To find out the clinical profile and association of Celiac Disease (CD) in children with established type-1 Diabetes Mellitus (T1DM) presenting a tertiary care hospital Karachi, Pakistan. METHODS: This cross-sectional study was conducted from January-2019 to July-2019 at National Institute Child Health, A total 126 T1DM patients age 1-18 years were subjected detailed history examinat...

CORRESPONDENCE Solid phase immunoassay for C trachomatis The development of chlamydial antigen detection kits has led to the wider availability of diagnostic services for this organism. Currently, two technologies are readily available; immunofluorescence microscopy and enzyme linked immunosorbant assay (EIA). Neither technology is perfect, with problems of sensitivity and of specificity.' Adva...

BACKGROUND Isoferulic acid (IFA), a naturally occurring cinnamic acid derivative, is a main active ingredient of the rhizoma of Cimicifuga dahurica. It has been shown various pharmacological activities. The aim of the study was to investigate the effect of IFA against MG-induced protein glycation and oxidative DNA damage. Free radical scavenging activity and the MGO-trapping abilities of IFA we...

background: streptokinase, which is injected intravenously with a standard dose of 1.5 miu, is the most widely used thrombolytic agent around the world. what is so important about this bioproduct is the level of antistreptokinase (anti-sk) antibody in the population, which is directly correlated to the incidence of streptococcal infections in that population. objective: since iran is an endemic...

aim : in this study, the prevalence of c. difficile , from patients with gastrointestinal complaints and its association with other enteropathogen microbes were investigated. background : clostridium difficile is an important pathogen associated with outbreaks of pseudomembranous colitis and other intestinal disorders, such as diarrhea. patients and methods : enterotoxin and cytotoxin (toxin a ...

OBJECTIVE Anti-endothelial cell antibodies in serum of patients with different inflammatory diseases can be detected by a whole cell enzyme-linked immunosorbant assay, using primary cultures of human umbilical vein endothelial cells. To avoid repeated isolation, it would be of great value if an immortal endothelial cell line could be used to perform anti-endothelial cell antibody assays. METH...

A panel of novel recombinant single-chain variable fragment (scFv) antibody against human immunodeficiency virus type-1 (HIV-1) was isolated and characterized. We generated human scFvs using RNA harvested from cervical B lymphocytes of Kenyan prostitutes who are highly exposed to HIV-1, but remain persistently seronegative. The variable regions of the heavy (VH) and light (VL) chain antibody ge...

background: nowadays, chlamydia trachomatis is known as a causative agent of infertility. because of, asymptomatic nature of infection, many may suffer from its lasting complications such as infertility. this study was performed in tehran during april 2007 to april 2008 to compare the prevalence of chlamydia trachomatis infection in fertile and infertile women using elisa and pcr methods. metho...

BACKGROUND Kaposi sarcoma (KS) may arise as a complication of kidney transplantation. In the Saint Luc Teaching Hospital in Brussels, patients of both Belgian and foreign origin are treated. The prevalence of human herpes virus 8 (HHV-8) infection differs in different geographical settings. We wanted to estimate the background infection rate and the risk of infection in our transplant populatio...

conclusions high hev seroprevalence (16.7%) was observed among the blood donors in bushehr province. it appears that exposure to hev increases with age; although, more people should be examined. results overall, 105 (16.7%) blood samples were positive for hev-specific-igg antibodies, while 523 (83.8%) were negative. the presence of anti-hev igg was not associated with gender; however, it was co...