Conjugated linoleic acid, better known as CLA, is a fatty acid derived from the required nutrient, linoleic acid. The major structural difference between linoleic acid (an 18 carbon, polyunsaturated fatty acid) and CLA, is that linoleic acid has double bonds at carbons 9 and 12 in a cis configuration (methylene interrupted), while CLA has numerous isomers without methylene interrupted conjugate...

objective(s): mindium laevigatum is an endemic plant of iran and turkey and is widely used as blood purifier, antiasthma and antidyspnea in traditional medicine. chemical composition of volatile materials of the plant and its antioxidant, antimicrobial and cytotoxic activities were reported in this study. materials and methods: simultaneous distillation-extraction (sde) and gc-mass-fid analysis...

Prostaglandin (PG) biosynthesis and kidney function was investigated in 24 adults (23 to 32 yr) during isocaloric formula diet periods, for 2 wk each, providing a linoleic acid supply of 0, 3, 3.5, 4, 6, 8, 13, 17, 18, or 20% of total energy intake. Total protein intake (15 energy %) was constant, as well as 5 g NaCl, 3 g KCl, and 0.6 g cholesterol per 2200 kcal formula diet. The amount of PG m...

Eighty patients with aorto-iliac/ femoro-popliteal atherosclerosis were collected to examine in detail their plasma cholesteryl ester fatty acid compositions and to compare them with the incidence of ischaemic heart disease through a 4-year follow-up. Various other biochemical and rheological parameters were also measured to see if these might explain any association between the abnormal fatty ...

BACKGROUND/AIM To comparatively investigate the effects of linoleic acid on convulsive and nonconvulsive epileptic seizures. MATERIALS AND METHODS Rats were divided into 3 groups: convulsive epileptic rats receiving only pentylentetrazole (PTZ) injections (group 1), convulsive epileptic rats receiving PTZ and linoleic acid (group 2), and Wistar Albino Glaxo rats from Rijswijk with genetic abs...

Biodegradable polymeric nanoparticles are widely recognized as efficacious drug delivery vehicles, yet the rational engineering of nanoparticle surfaces in order to improve biodistribution, reduce clearance, and/or improve targeting remains a significant challenge. We have previously demonstrated that an amphiphilic conjugate of avidin and palmitic acid can be used to modify poly(lactic-co-glyc...

Objective(s): Mindium laevigatum is an endemic plant of Iran and Turkey and is widely used as blood purifier, antiasthma and antidyspnea in traditional medicine. Chemical composition of volatile materials of the plant and its antioxidant, antimicrobial and cytotoxic activities were reported in this study. Materials and Methods: Simultaneous distillation-extraction (SDE) and GC-Mass-FID analysis...

The essentiality of the n-6 fatty acid, linoleic acid, was established about 80 years ago; the essentiality of the n-3 analogue, a-linolenic acid, became accepted rather later. The intakes of these fatty acids necessary to avoid deficiency are quite low (estimated to be 1 and 0·2 % of energy intake, respectively, corresponding to intakes in adults of about 2 and 0·4 g/d), and all diets should o...