Background: Histopathology is a cornerstone of diagnostics in Sjögren`s syndrome (SjS). The current widely accepted standard, minor salivary gland (lip) biopsy, surgical procedure with several disadvantages including permanent sensory loss the lips as well-known complication (reviewed 1). Moreover, lymphoma glands cannot be excluded. Ultrasound-guided core needle biopsy (CNB) an excellent diagn...

lip pits are among the rarest congenital deformities recorded. initially reported in 1845, it’s familial occurrence has been reported just once. these developmental anomalies occur either as an isolated defect or in association with other developmental deformities including cleft lip, cleft palate or both. it may be located at the commisures of the lips or in the midline of the lower lip. it is...

We report a case of AILD and sicca syndrome. The patient had presented with renal insufficiency, lymphadenopathy, hepatosplenomegaly, polyclonal hypergammaglobulinaemia, dryness of the eyes and mouth. Lip biopsy specimens showed an unusual cellular infiltrate similar to his kidney lesions. Data from the eight previously reported cases support the hypothesis that the association is a distinct pa...

BACKGROUND Vermilion irregularities are common secondary deformities after cleft lip repair, regressed or resected hemangiomas, trauma and tumor surgeries. Vermilion deficiency attracts considerable attention and detracts from an otherwise excellent lip repair. Minor and moderate vermilion defects can be corrected with upper lip advancement, rotation flaps, tongue flaps or grafts. Major defect...

Plasmoacanthoma is an extremely rare verrucous tumor located on periorificial regions characterized by dense dermal plasmacytic infiltrates. Some authors classify it as a form of reactive plasma cell proliferation which represents a heterogeneous spectrum of mucocutaneous disorders. These plasma cell proliferations have been considered to be a benign immunologic inflammatory reaction to known o...

We report two brothers of Chinese origin who have an apparently unique syndrome of cleft lip/palate, profound sensorineural deafness, and a sacral lipoma. Additional findings which were not common to both were aberrant digital appendages on the heel and thigh of one boy and an anterior sacral meningocele and dislocated hip in the other. Intelligence is normal in both. Both boys suffer from func...

We report a 9-year-old Japanese girl who presented with muscle weakness and elevated serum levels of muscle-derived enzymes following mycoplasma infection. Rhabdomyolysis or myositis was suggested by magnetic resonance imaging and repeated four times within 4 years. Each episode developed following respiratory infection and spontaneously recovered. The diagnosis of Sjögren’s syndrome was made b...

A needle is described for obtaining specimens of non weight-bearing hyaline cartilage from the lateral femoral condyle. The hyaline cartilage of the femur continues onto the lateral surface of the condyle as a 'lip' which lies deep to the capsule of the knee joint and is readily accessible for biopsy. The cylindrical needle is hollow with a sharpened cutting edge and is 5 mm. in diameter. Withi...