Animals given transplants of the MAC16 colon adenocarcinoma show a progressive decrease in carcass weight as the tumor size increases without a reduction in either fluid or caloric intake when compared with non-tumor-bearing controls. There is a decrease in both carcass fat and muscle mass which is directly proportional to the weight of the tumor. In male animals weight loss occurs when the tum...

A lipolytic screening with fungal strains isolated from lignocellulosic waste collected in banana plantation dumps was carried out. A Trichoderma harzianum strain (B13-1) showed good extracellular lipolytic activity (205 UmL-1). Subsequently, functional screening of the lipolytic activity on Rhodamine B enriched with olive oil as the only carbon source was performed. The successful growth of th...

The aim of the present study was to gain insight into the signaling pathway used by leptin to stimulate lipolysis. The lipolytic rate of white adipocytes from sex- and age-matched lean (+/+) and fa/fa rats was determined in the absence or presence of leptin together with a number of agents acting at different levels of the signaling cascade. Leptin did not modify FSK-, dbcAMP-, and IBMX-stimula...

Bio-deteriorated waste is the leftover organic matter of unwanted raw food which if not handled properly or left for natural degradation can cause health issues. Microorganisms have ability to biodegrade by secreting enzymes. The aim work was isolate and identify lipase-producing bacteria from polluted (Bio-deteriorated Municipal Solid Waste) dumping sites Gandhinagar, Gujarat, India. Lipase-pr...

Lipolytic activities of eight stereoisomers of pentapeptide, histidyl-phenylalanylarginyl-tryptophyiglycine, corresponding to the positions 6•`10 in the NH2-terminal portion of ACTH were assayed in vitro. All the isomers were active in the experiment using rat epididymal fat. However, three isomers, all-D, L-His-L-Phe-L-Arg-D-Trp-Gly, and D-His-D-Phe-D-Arg-L-Trp-Gly, were inactive in rabbit per...

BACKGROUND Adipocytes in femoral areas are known to be metabolically 'silent'. Changes related to fat cell hypertrophy may be involved in the formation of cellulite. A mechanical massage technique, with circulatory and dermotrophic properties, has been shown to have an impact on clinical evaluations (i.e. changes in morphometric measurements) in cellulite areas. Whether this technique affected ...

Microorganisms can easily degrade agro-industrial wastes in a solid-state fermentation process thereby synthesizing many important commercial bio compounds including lipolytic enzymes. Screening different habitats for bacteria with lipase activity and optimizing its parameters facilities effective production usage industries. In this study, soil samples from Abattoirs Kaduna metropolis were scr...

Loss of fat mass is a key feature of cancer cachexia and has been attributed to increased adipocyte lipolysis. The mechanism behind this alteration is unknown and was presently investigated. We studied mature s.c. fat cells and differentiated preadipocytes from 26 cancer patients with and without cachexia. Hormone-induced lipolysis and expression of lipolysis-regulating genes were determined to...