BACKGROUND An economic analysis from the perspective of the UK National Health Service (NHS) evaluated the cost effectiveness of lisdexamfetamine dimesylate (LDX) compared with atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder who have had an inadequate response to methylphenidate. METHODS A 1-year decision-analytic model was constructed, with the health ou...

INTRODUCTION Binge eating disorder (BED), a formal eating disorder diagnosis in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), is characterized by recurrent binge eating, marked distress about binge eating, and the absence of extreme weight compensatory behaviors. BED is more prevalent than other eating disorders, with broader distribution across age, sex and ethnic/racial g...

This study evaluated the efficacy and safety of lisdexamfetamine dimesylate (LDX) compared with placebo in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) in Europe. Osmotic-release oral system methylphenidate (OROS-MPH) was included as a reference arm. Patients (6-17 years old) with a baseline ADHD Rating Scale version IV (ADHD-RS-IV) total score ≥ 28 were randomi...

BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral psychiatric disorder that afflicts children, with a reported prevalence of 2.4% to 19.8% worldwide. Stimulants (methylphenidate [MPH] and amphetamine) are considered first-line ADHD pharmacotherapy. MPH is a catecholamine reuptake inhibitor, whereas amphetamines have additional presynaptic activity. Although ...

Social networking sites are visibly the latest trend and have changed the way the 21st century communicates each other. Its usage becomes more and more in the world of information, its presence in the library and information science becomes challenging and exciting. The aim of this study was to know the trend of posting, sharing, commenting and like a Facebook post, to understand the participat...

Hydraulický lis so systémom LS pre modelovaniu procesov plastických deformácií At first, the paper describes destination of the presented hydraulic press. Next, the substance of load sensing (LS) systems’ operation was introduced, and electro-hydraulic system of this type, installed in laboratory hydraulic press, was described. The control and measurement circuit of the device was also describe...

Lis Bodil Karlsson, Elisabeth Rydwik Department of Social and Psychological Studies, Karlstad University, Karlstad, Sweden Research and Development Unit, Jakobsberg’s Hospital, Stockholm County Council, Järfälla, Sweden Deptartement of Neurobiology, Care Sciences and Society, Division for Physiotherapy, Karolinska Institute, Huddinge, Sweden Email: [email protected], [email protected]...

BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder in children, with worldwide prevalence of ADHD varying from 5.9 to 7.1 %, depending on the reporter. In case of inadequate response to stimulants, combination therapy of stimulants and an adjunctive medication may improve the control of ADHD symptoms, reduce the dose-limiting adverse events, and help con...

BACKGROUND Following the approval of lisdexamfetamine dimesylate (LDX) in several European countries for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents with an inadequate response to methylphenidate (MPH) treatment, the aim of the present analysis was to establish the response to LDX in subgroups of patients with different ADHD medication histories....