Pork liver contains an endogenous enzyme, ferrochelatase (FeCH), which catalyses the formation of zinc protoporphyrin (ZnPP), a natural pigment great interest for meat industry. The aim this study was to analyse effect pork drying (from −10 70 °C), as stabilisation method, on FeCH activity (EA) and apparent concentration (EC app ). Drying temperatures close room conditions 10 20 °C) allowed pre...

results almost 8% of the personnel showed positive tst (over 10 mm) reaction while 29% of them had considerable t - cell reactivity against ppd in elispot assays. however, the esat - 6 reactivity was found only in one case of hcws. no correlation was found between the patterns of the reactions and the age or the duration of the employment or previous vaccination history of the participants. the...

SULFORAPHANE PREVENTS ACETAMINOPHEN-INDUCED HEPATIC INJURY IN MICE Robin H. Schmidt 11/29/2011 Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is known to confer antioxidant protection in vivo. Rather than directly reacting with free radicals, however, SFN works by inducing Nrf2, a transcription factor that binds to the promoter regions of several known antioxidant genes ...

In a preceding article (1), the distribution of acid phosphatase activity was studied in a number of fractions separated from rat liver homogenates by differential centrifugation. It was found that less than 5 per cent of the enzymatic activity separates with the nuclear fraction, while over 90 per cen t remains associated with the cytoplasmic components. Among the latter, the mitochondria and ...

Glutamate dehydrogenase has been purified and crystallized from rat liver mitochondria and from whole rat liver preparations. No differences in the enzyme prepared by the two different methods have been observed and there is no evidence that more than one glutamate dehydrogenase occurs in rat liver. The pure enzyme has a molecular weight of 350,000 f 20,000 and consists of six to eight subunits...

We herein report two cases of drug-induced liver injury (DILI) due to mosapride. Case 1: A 78-year-old man was admitted with elevated transaminase levels. The cessation of mosapride led to the improvement of elevated liver enzyme levels. Case 2: A 54-year-old man was admitted with jaundice. Mosapride was discontinued immediately, and methylprednisolone was administered for acute liver failure. ...

Background: Recently, applications of nanoparticles in many fields of medicine have been developed, due to their specific physical and chemical properties. Therefore assessment of their toxicity specially in the in vivo condition is necessary. Objectives: The aim of this study is to evaluation the effect of Fe3O4 nanoparticles coating by biocompatible compounds on their t...