i ntroduction: deep and long-lasting anesthesia is essential throughout endodontic treatment. this study was conducted to compare the effect of adding fentanyl to epinephrine-containing lidocaine on depth and duration of local anesthesia in painful maxillary molars with irreversible pulpitis (irp). methods and materials: this randomized double-blind, clinical trial with parallel design was cond...

BACKGROUND AND PURPOSE There has recently been interest in the advantages of minimally invasive surgery (MIS) over conventional surgery, and on local infiltration analgesia (LIA) during knee arthroplasty. In this randomized controlled trial, we investigated whether MIS would result in earlier home-readiness and reduced postoperative pain compared to conventional unicompartmental knee arthroplas...

A local anaesthetic block of branches of the greater auricular and auriculotemporal nerves was used to facilitate the extraction of retained butterfly backs and ear-ring studs. A total of 28 ear blocks were performed on 26 patients. Two patients required bilateral ear blocks, and 17 earlobes were infected. Complete analgesia was obtained in 25 cases, and two patients complained of tolerable dis...

Local infiltration analgesia (LIA) has been introduced recently as a promising step forward in reducing postoperative pain and side effects from analgesics after knee arthroplasty and, so far, with less convincing results after hip artroplasty. As often with new methods, there is a way to go from the first, enthusiastic, nonblinded case series to evidencebased recommendations for clinical, ever...

BACKGROUND Postoperative inflammation following total hip arthroplasty (THA) can lead to delayed mobilization and return of hip function. Our primary aim was to assess whether local infiltration analgesia (LIA) during surgery can prevent postoperative inflammation. METHODS This is a sub-analysis of data from a broader double-blind study where 56 patients received spinal anaesthesia for THA. A...

BACKGROUND Total knee arthroplasty (TKA) is one of the most commonly performed procedures while postoperative analgesia still remains challenging. The efficacy and safety of local infiltration analgesia (LIA) versus regional blockade (RB; epidural analgesia and/or peripheral nerve block) for pain management after TKA are controversial. OBJECTIVES The purpose of this meta-analysis was to deter...

BACKGROUND Transversus abdominis plane (TAP) infiltration has been increasingly used for postsurgical analgesia in abdominal/pelvic procedures; however, duration/extent of analgesia with standard local anesthetics is limited. This pilot study assessed the preliminary efficacy and safety of two volumes of liposome bupivacaine administered via TAP infiltration in patients undergoing robotic lapar...

The tumescent technique involves the injection of large volumes of dilute local anaesthetic such as lidocaine or bupivacaine, with or without adrenaline solution, into subcutaneous fat, obtaining swelling and firmness (tumescence) of the surgical area and also creating regional anaesthesia of the skin and subcutaneous tissue that allows cutaneous surgery without pain. In particular, in cutaneou...