نتایج جستجو برای: long qt syndrome
تعداد نتایج: 1359864 فیلتر نتایج به سال:
P rolongation of the QT interval is a serious electrocardiogram finding because of its association with torsades de pointes and sudden cardiac death. Both congenital and acquired factors can lead to abnormal lengthening of the QT interval. Six types of congenital long QT syndrome (LQT1– LQT6) have been described, each involving mutations in genes encoding potassium or sodium transmembrane chann...
BACKGROUND Epinephrine infusion may unmask latent genetic conditions associated with cardiac arrest, including long-QT syndrome and catecholaminergic polymorphic ventricular tachycardia (VT). METHODS AND RESULTS Patients with unexplained cardiac arrest (normal left ventricular function and QT interval) and selected family members from the Cardiac Arrest Survivors with Preserved Ejection Fract...
T o those of us who were practicing cardiology in the early 1960s, the reports from Jervell and Lange-Nielsen,1 Romano and colleagues,2 and Ward3 were welcome enlightenment for a few of our patients with alarming episodes of syncope and a family history of sudden death. Although Ward reported that one of his original patients responded to ,8-blockade and that form of therapy remains central to ...
The syndrome of long QT interval frequently follows to syncope or a sudden cardiac death on the basis of originated polymorphic ventricular tachycardia of the "torsade de pointes" type. The prolongation of the QT interval in the hereditary form is based on mutation of the genes responsible for the formation of sodium and potassium channels. The authors analyze the occurrence, clinical findings,...
A Study to Determine if T Wave Alternans is a Marker of Therapeutic Efficacy in the Long QT Syndrome
T wave alternans (TWA), an alteration of the amplitude and morphology of the T wave that occurs every-other-beat, is emerging as an important new marker for identifying patients at risk of developing malignant ventricular arrhythmias. {Rosenbaum, Jackson, et. Al 1994} It is undergoing intense investigation in a number of areas where patients are thought to be at higher risk for Sudden Cardiac D...
OBJECTIVES This study was designed to investigate the clinical course of women with long QT syndrome (LQTS) throughout their potential childbearing years. BACKGROUND Only limited data exist regarding the risks associated with pregnancy in women with LQTS. METHODS The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after ...
The long QT syndrome (LQTS) is a rare, congenital or acquired disease, which may lead to fatal cardiac arrhythmias (torsade de pointes, TdP). In all LQTS subtypes, TdPs are caused by disturbances in cardiac ion channels. Diagnosis is made using clinical, anamnestic and electrocardiographic data. Triggers of TdPs are numerous and should be avoided perioperatively. Sufficient sedation and preoper...
The drug-induced long QT syndrome is a distinct clinical entity that has evolved from an electrophysiologic curiosity to a centerpiece in drug regulation and development. This evolution reflects an increasing recognition that a rare adverse drug effect can profoundly upset the balance between benefit and risk that goes into the prescription of a drug by an individual practitioner as well as the...
The patient was a 71-year-old female with Torsade de Pointes (TdP) associated with idiopathic long QT syndrome. TdP and polymorphic nonsustained VT were frequently observed at bedside and an electrophysiologic study was performed. The QT (and QTU) interval was abnormally prolonged, and alteration of the QT interval was also recorded on the electrocardiogram. Monophasic action potential (MAP) fr...
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