Splicing is a predominantly co-transcriptional process that has been shown to be tightly coupled to transcription. Chromatin structure is a key factor that mediates this functional coupling. In light of recent evidence that shows the importance of higher order chromatin organization in the coordination and regulation of gene expression, we discuss here the possible roles of long-range chromatin...

Complex networks can usually be divided in dense subnetworks called communities. In evolving networks, the usual way to detect communities is to find several partitions independently, one for each time step. However, this generally causes troubles when trying to track communities from one time step to the next. We propose here a new method to detect only one decomposition in communities that is...

This paper introduces the use of dynamic features for robust target recognition of ground vehicles. Most current approaches rely on instantaneous spectral features such as those derived from harmonically related spectral lines. Significant drawback of these approaches are that the use of low amplitude (10-20dB below dominant line) spectral lines severely limit classification range. The stronges...

The large number of L1 [long interspersed elements (LINE)-1] sequences found in the genome is due to the insertion of copies of the retrotransposon over evolutionary time. The majority of copies appear to be replicates of a few active, or "master" templates. A continual replacement of master templates over time gives rise to lineages distinguishable by their own unique set of shared-sequence va...

Superior mirages of simple appearance are occasionally observed over distances exceeding 70 km. These mirages cannot be explained in terms of standard textbook models; rather, they are shown to arise from fairly complex atmospheres. Two observations of different types, observed at Resolute Bay, Canada, are presented. The first is the basic three-image mirage in which one inverted and one erect ...

Electrons have so little mass that in less than a second they can tunnel through potential energy barriers that are several electron-volts high and several nanometers wide. Electron tunneling is a critical functional element in a broad spectrum of applications, ranging from semiconductor diodes to the photosynthetic and respiratory charge transport chains. Prior to the 1970s, chemists generally...

Decoding neural algorithms is one of the major goals of neuroscience. It is generally accepted that brain computations rely on the orchestration of neural activity at local scales, as well as across the brain through long-range connections. Understanding the relationship between brain activity and connectivity is therefore a prerequisite to cracking the neural code. In the past few decades, tre...

Background: Vulvovaginal Candidiasis is one of the most common vaginal infections and identification of candida species can be helpful in medical treatment. Intra uterine devices (IUDs) are effective, long-term methods of contraception, which in some cases may lead to Vulvovaginal Candidiasis. This study was developed to assess the effect of IUD insertion on Candida fungal flora in cervicovagin...