Locally advanced prostate cancer (LAPC) is defined as histologically proven T3-4 prostatic adenocarcinoma. In this review, we define the individual roles of radiotherapy (RT), short-term (ST-) and long-term (LT-) androgen deprivation therapy (ADT), and their combination in multimodal therapy for LAPC. Despite limitations in comparing the clinical outcomes among published papers, in the present ...

Repetitive transcranial magnetic stimulation (rTMS) is a widely-used method for modulating cortical excitability in humans, by mechanisms thought to involve use-dependent synaptic plasticity. For example, when low frequency rTMS (LF rTMS) is applied over the motor cortex, in humans, it predictably leads to a suppression of the motor evoked potential (MEP), presumably reflecting long-term depres...

Light field (LF) images can be used to improve the performance of image super-resolution (SR) because both angular and spatial information is available. It challenging incorporate distinctive from different views for LF SR. Moreover, long-term previous layers weakened as depth network increases. In this paper, we propose a dense dual-attention Specifically, design view attention module adaptive...

OBJECTIVE Previous studies on short-term time series of heart rage suggest an inverse relationship between age and spectral powers of heart rate variability in various frequency bands. In this study, we examined the relationship between age (6-61 years) and long-term heart rate variability. METHODS We obtained 24-h Holter ECG in 33 healthy human subjects (11 children and 22 adults). The heart...

we aimed to evaluate clinical, high resolution computed tomography (hrct) and pulmonary function test (pft) findings after 18-23 years of exposure in veterans of sulphur mustard (sm) exposure. we performed a cross-sectional study of 106 patients. inclusion criteria were 1: documented exposure to sm as confirmed by toxicological analysis of their urine and vesicular fluid after exposure 2: singl...

the influence of long-term mixed organic and inorganic contamination on soil microbial activity, community structure and genetic diversity was investigated in soil samples from a coke oven plant located in upper silesia, poland. the tested soils were heavily contaminated with polycyclic aromatic hydrocarbons (pahs) and heavy metals. the microbial communities were characterized using the phospho...

introduction: langerhans cell histiocytosis (lch) is a rare disease characterized by clonal prolifera-tion of histiocytosis in different tissues. permanent consequences (pc) described among subjects with langerhans cell histiocytosis (lch).in this study we report the prevalence of permanent sequel among long – term survivors of lch in our center. methods: we had 30 cases of lch from 1989 – 2001...

Obesity, dyslipidemia, hyperglycemia/type II diabetes and hypertension together constitute the so-called metabolic syndrome. Frequency of occurrence of these serious metabolic disturbances is associated with life style and is on the rise in prosperous industrialized countries. These diseases represent not only a serious health problem but also social and economic ones, and involve in prophylaxi...

Introduction. A significant percentage of the musculoskeletal system pathology in children is currently fall on foot – longitudinal flatfeet, which not only a medical, but also social problem. The incidence this up to 58% total orthopedic pathology.
 Traditional methods treatment and prevention mild (I– II severity) flatfeet (LF), are known today (massage, physiotherapy exercises, use devi...

background: spermatogonial stem cells are subpopulation of spermatogonial cells in testis tissue that support beginning and maintenance of spermatogenesis. ubiquitin carboxy-terminal hydrolase l1 (uchl1) could be a specific marker for identification of spermatogonial stem cells including spermatogonial sperm cells (sscs) in testis tissue and during the culture; therefore we undertook this study...