One of the basic assumptions of the classical dynamic lot-sizing model is that the aggregate demand of a given period must be satisfied in that period. Under this assumption, if backlogging is not allowed then the demand of a given period cannot be delivered earlier or later than the period. If backlogging is allowed, the demand of a given period cannot be delivered earlier than the period, but...

In this paper we study an integrated lot sizing problem with distribution and delivery time windows in which the producer has the choice to locate distribution centers from where products are stored and shipped to customers. Based on a real case study, we describe, model, and solve this rich integrated lot sizing problem. In this integrated optimization application, we consider a multi-plant, m...

Since that a job usually contains several working procedures in actual production, and it’s hard to optimize the flexible collaborative planning, the flexible lot splitting and scheduling of the job simultaneously in batch production mode, a model for multiobjective integration of flexible collaborative planning and fuzzy lot-splitting scheduling is established. We take four performance indicat...

    inventory model,   backorder   buyer ,   vendor,   lot for lot policy In this paper, an inventory model for two-stage supply chain is investigated. A supply chain with single vendor and single buyer is considered. We assume that shortage as a backorder is allowed for the buyer and the vendor makes the production set up every time the buyer places an order and supplies on a lot for lot basis...

One of the basic assumptions of the classical dynamic lot-sizing model is that the aggregate demand of a given period must be satisfied in that period. Under this assumption, if backlogging is not allowed then the demand of a given period cannot be delivered earlier or later than the period. If backlogging is allowed, the demand of a given period cannot be delivered earlier than the period, but...

abstractgene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. one promising form of gene delivery system (dds) is liposomes. the success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. liposomal gene delivery systems...

although lot streaming scheduling is an active research field, lot streaming flexible flow lines problems have received far less attention than classical flow shops. this paper deals with scheduling jobs in lot streaming flexible flow line problems. the paper mathematically formulates the problem by a mixed integer linear programming model. this model solves small instances to optimality. moreo...

this paper deals with the single machine multi-product lot scheduling problem in which defective items are produced in any production run of each product. we have adopted the common cycle scheduling policy and assumed that the setup times for production of each product can be non-zero. further, we have assumed that defective items will be reworked and the inspection costs during the normal prod...