Meloxicam (MLX) has poor water solubility which leads to slow absorption following oral administration; hence, immediate release tablet is unsuitable in the treatment of acute pain. The aim of this study was to prepare a novel fast ultra-fine self-nanoemulsifying drug delivery system (UF-SNEDDS) of MLX for oral administration to facilitate drug release process in the stomach as well as comparin...

Ultrafine (Uf) particles are a component of particulate air pollution suggested to be responsible for the health effects associated with elevations of this pollutant. We have previously suggested that Uf particles, through the induction of oxidative stress, may induce inflammation in the lung, thus exacerbating preexisting illness in susceptible individuals. Alveolar macrophages are considered ...

A comparison was made of the bronchoalveolar lavage fluid (BALF) response to ultrafine nickel (Uf-Ni) and standard-sized nickel (Std-Ni). Rats were intratracheally instilled with 0, 0.1, 0.5, 1 and 5 mg Uf-Ni and Std-Ni, respectively. At 3 d after instillation, the body weight and wet lung weight were determined. At the same time, BALF was analyzed for lactate dehydrogenase (LDH), total protein...

BACKGROUND Maintenance dialysis therapy is the only way to remove excess fluid in patients with anuric end-stage renal disease. The optimal ultrafiltration (UF) volume in patients on peritoneal dialysis (PD) remains controversial. METHODS We retrospectively analysed a cohort of 86 prevalent anuric PD patients followed up for a median of 25.3 months (range, 6 to 54 months). Clinical and PD par...

Endothelial protein kinase C (PKC) signaling was investigated in different regions of normal porcine aorta. The locations map to differential atherosclerotic susceptibility and correlate with sites of disturbed (DF) or undisturbed (UF) local flow profiles. Endothelial lysates were isolated from the inner curvature of the aortic arch (DF; athero-susceptible) and a nearby UF region of the descend...

economical way of producing an on-line pharmaceutUltrafiltration (UF ) is a membrane filtration process ical grade solution (sterile and non-pyrogenic) used based on a molecular sieving exclusion [1]. The use of for substitution fluid. In this case, UF acts as a ‘cold UF in renal replacement therapy (RRT) has been sterilizing’ process. (ii) The enhanced blood purificareported in various fields ...

Straw powders were blended with hydrolyzed soy protein isolate (HSPI) modified urea-formaldehyde (UF) resins to produce biodegradable seedling containers. The tensile strength and the degradability of the seedling containers were characterized. Moreover, the degradation behavior of modified UF resins was investigated using N isotopic tracing, dynamic mechanical analysis, C CP/MAS NMR spectrosco...

The use of ultrafiltration technology for municipal drinking water applications is a relatively recent concept, although in the beginning, it is already commonly used in many industrial applications such as food or pharmaceutical industries. Ultrafiltration is proven to be a competitive treatment compare with conventional ones. In some cases, the combination of ultrafiltration with conventional...

Comparison of two commonly used techniques for molecular weight determination of natural organics, ultrafiltration (UF) fractionation and high-performance size exclusion chromatography (SEC), shows that neither technique gives absolute measures of molecular weight. Investigations of International Humic Substances Society standard humic and fulvic acids as well as natural organic matter concentr...

BACKGROUND Increased serum concentrations of macroprolactin are a relatively common cause of misdiagnosis and mismanagement of hyperprolactinemic patients. METHODS We studied sera from a cohort of 42 patients whose biochemical hyperprolactinemia was explained entirely by macroprolactin. Using 5 pretreatments, polyethylene glycol (PEG), protein A (PA), protein G (PG), anti-human IgG (anti-hIgG...