U.S. Military Global Health Engagement is evolving toward more specifically military strategic objectives, as well as better coordination with U.S. diplomacy and international development. The Department of Defense (DoD) issued policy guidance on global health engagement codifying these priorities for the first time in 2013, and is now developing the corresponding implementing instructions and ...

BACKGROUND Very high levels of ionizing radiation exposure have been associated with the development of soft-tissue sarcoma. The effects of lower levels of ionizing radiation on sarcoma development are unknown. This study addressed the role of low to moderately high levels of ionizing radiation exposure in the development of soft-tissue sarcoma. METHODS Based on the Life Span Study cohort of ...

BACKGROUND The growing use of imaging procedures in the United States has raised concerns about exposure to low-dose ionizing radiation in the general population. METHODS We identified 952,420 nonelderly adults (between 18 and 64 years of age) in five health care markets across the United States between January 1, 2005, and December 31, 2007. Utilization data were used to estimate cumulative ...

The radiation environment in deep space, where astronauts are behind the shelter provided by the Earth’s magnetosphere, is a major health concern. Galactic cosmic rays (GCR) and solar particle events (SPE) are two basic sources of space radiation in the solar system. The health risks of exposure to high levels of space radiation can be observed either as acute and delayed effects. Zhang et al. ...

Previous epidemiologic data demonstrate that cardiovascular (CV) morbidity and mortality may occur decades after ionizing radiation exposure. With increased use of proton and carbon ion radiotherapy and concerns about space radiation exposures to astronauts on future long-duration exploration-type missions, the long-term effects and risks of low-dose charged particle irradiation on the CV syste...

Buratovic, S. 2015. Neonatal Exposure to Low-Dose Ionizing Radiation in Mice: Developmental neurotoxic effects of single and fractionated doses and interaction with nicotine. 38 pp. Uppsala This thesis aims to investigate the developmental neurotoxic effects of low-dose exposure to ionizing radiation, alone or together with nicotine, during a defined critical period of neonatal brain developmen...

Empirical information on the effects of low doses of ionizing radiation is beset by severe limitations. Theoretical considerations of biophysics can guide the analysis of epidemiological data by indicating certain dose-response relations or eliminating others. Thus, it can be shown that at low doses there must be proportionality between dose and effect on non-interacting cells and that one must...

Exposure to ionizing radiation (IR) is inevitable to humans in real-life scenarios; the hazards of IR primarily stem from its mutagenic, carcinogenic, and cell killing ability. For many decades, extensive research has been conducted on the human cell responses to IR delivered at a low dose/low dose (LD) rate. These studies have shown that the molecular-, cellular-, and tissue-level responses ar...

The report's focus is low-dose, low-LET — "linear energy transfer" — ionizing radiation that is energetic enough to break biomolecular bonds. In living organisms, such radiation can cause DNA damage that eventually leads to cancers. However, more research is needed to determine whether low doses of radiation may also cause other health problems, such as heart disease and stroke, which are now s...