Hepatic triglyceride lipase (HL) is thought to play a role in the formation of low density lipoproteins (LDLs) from small very low density lipoproteins (VLDLs) and intermediate density lipoproteins (IDLs). To analyze the possible physiological role of HL in determining LDL buoyancy, size, and chemical composition, HL activity and LDL were studied in 21 patients with coronary artery disease (CAD...

in russia (formerly ussr) study of biomodulation action (bma) mechanisms of low-intensity laser irradiation (lili) began in 1964, immediately after the development of lasers. during the period from 1965 to 1972 several dozens of scientific conferences were held, hundreds of studies were published. generally, secondary mechanisms and results of lili effect on patients with various diseases were ...

Increased hepatic lipase (HL) activity is associated with small, dense, low density lipoprotein (LDL) and low high density lipoprotein2 (HDL2) cholesterol (-C) levels. A polymorphism in the promoter region of the HL gene (LIPC) is associated with HDL-C levels. To test whether this association is mediated by differences in HL activity between different LIPC promoter genotypes, the LIPC promoter ...

Hepatic lipase (HL) is thought to play a role in processing very low density lipoprotein to low density lipoprotein (LDL). To analyze the relationship between HL and LDL, the density, size, and chemical composition of LDL isolated from 18 normal subjects and from three subjects with reduced or absent levels of HL activity were compared. In an HL-deficient subject, the major peak of apoprotein (...

background: one of the most important indicators in public health is earlier traits of new born specially birth's weight. the aim of this study was determined effects of biological and psychological traits mothers on low birth weight in isfahan province. methods: this research performed on 910 new born and delivered mothers of isfahan province in 2009. according to the percentage of population ...

background: about 21 millions premature and low birth weight (lbw) infants are born in the world every year where the majority of them are in the middle east countries. the literatures have shown that lbw infants and premature infants have a smaller chance to survive than the normal ones. this research carried out to determine the situation of catch up growth of lbw infants in comparison with n...

Association of hepatic lipase (HL) with pure heparan sulfate proteoglycans (HSPG) has little effect on hydrolysis of high density lipoprotein (HDL) particles, but significantly inhibits (>80%) the hydrolysis of low (LDL) and very low density lipoproteins (VLDL). Lipolytic inhibition is associated with a differential ability of the lipoproteins to remove HL from the HSPG. LDL and VLDL are unable...

OBJECTIVE Increased expression of human hepatic lipase (HL) or a catalytically inactive (ci) HL clears plasma cholesterol in mice deficient in low-density lipoprotein receptors (LDLr) and murine HL. We hypothesized that increased expression of both HL and ciHL reduces atherosclerosis in these mice. METHODS AND RESULTS Mice deficient in both LDLr and murine HL, alone or transgenically expressi...

A new inhibitor of acyl CoA:cholesterol acyltransferase (ACAT), HL-004 [N-(2, 6-diisopropylphenyl)tetradecylthioacetamide], suppressed the synthesis of cholesterol [14C]oleate at 10(-9) approximately 10(-7) M in a concentration-dependent manner in both THP-1 cell-derived macrophages and foam cells prepared from aortic intima of rabbits fed a high cholesterol diet. Incorporation of [3H]cholester...