BACKGROUND Low-intensity pulsed ultrasonography (LIPUS) is a form of mechanical stimulation that is delivered via a special device to the fracture site for the acceleration of fracture healing. We conducted a meta-analysis to assess the effect of LIPUS for fresh fractures in adults. METHODS MEDLINE, EMBASE and the Cochrane Library searched between Jan 1980 and Nov 2016. Studies should be quas...

Brain stimulation techniques are important in both basic and clinical studies. Majority of well-known brain stimulating techniques have low spatial resolution or entail invasive processes. Low intensity focused ultrasound (LIFU) seems to be a proper candidate for dealing with such deficiencies. This review recapitulates studies which explored the effects of LIFU on brain structures and its func...

Background/introduction Low Intensity Focused Ultrasound (LIFU) continues to gain traction in the field of non-invasive neuromodulation. Recent in vivo rat studies suggest that LIFU can be used to modulate region-specific brain activity in the motor cortex, leading investigators to conclude that LIFU may be a better alternative to more prominent, and more invasive, mechanisms of neuromodulation...

INTRODUCTION: Many trauma surgeries and reconstructive surgeries involve re-establishment of a bone-tendon (B-T) junction, such as repair of patella fractures. In case of comminuted patella fractures, partial patellectomy has become a option of surgical repair . But direct B-T junction repair is slow due to poor regenerative capability of its junctional fibrocartilage zone. Biophysical interven...

Introduction Low-intensity pulsed ultrasound (LIPUS) has been reported, by various authors, to promote bone healing. The aim of our review was to review the available literature and evaluate the effectiveness of LIPUS in the treatment of various types of complicated fracture union. Materials and methods Different search engines including MEDLINE, EMBASE and the Cochrane Library were used, and t...

This study presents two novel theoretical models to elucidate frequency sensitive nuclear mechanisms in low-intensity ultrasound enhanced bioeffects. In contrast to the typical 1.5 MHz pulsed ultrasound regime, our group previously experimentally confirmed that ultrasound stimulation of anchored chondrocytes at resonant frequency maximized gene expression of load inducible genes which are regul...

BACKGROUND Low-intensity pulsed ultrasound (LIPUS) has been shown to stimulate tissue metabolism and accelerate muscle healing. However, the optimal parameters in the use of LIPUS are still not clear. OBJECTIVE The aim of this study was to analyze the effects of LIPUS on muscle healing in rats subjected to a cryolesion. METHOD Twenty rats were divided into the following groups: an injured c...

The low-intensity ultrasound that is used in clinical diagnoses, such as abdomen echo inspection, is a non-invasive treatment, and penetrates deeper into the body than light. Recently, sonodynamic therapy (SDT), which uses low-intensity ultrasound together with a sonosensitizer, has been developed for cancer therapy in applying such properties of ultrasound. So far, most sonosensitizers that ha...

INTRODUCTION Ultrasound has proven to be an important therapeutic resource regarding musculoskeletal disease and is routinely used in physical therapy and medicine both therapeutically and diagnostically. The aim of the present study was to analyse the effects with different ultrasound intensities in order to establish the ideal radiation level in cell cultures. MATERIAL AND METHODS FIBROBLAS...

Low-intensity ultrasound is a biophysical form of intervention in the fracture-repair process, which through several mechanisms accelerates healing of fresh fractures and enhances callus formation in delayed unions and nonunions. The goal of this review is to present the current knowledge obtained from basic science and animal studies, as well as existing evidence from clinical trials and case ...