fifty-seven patients suffering from systemic lupus erythematosus with different clinical features were studied from various aspects of immunological abnormalities, including anti-nuclear antibodies; anti-dna; anti-sm (smith's antigen); and, other extractable nuclear antigens. the tests employed were microhemagglutination, counter immunoelecterphoresis, and radio immunoassay (ria). the compariso...

Background: Systemic Lupus Erythematosus is a kind of multi-system autoimmune disorder with unknown aetiology and it produces antibodies against various tissues. Case Presentation:The patient wasa 44-year-old woman with a history of Systemic Lupus Erythematosus for approximately five years, along with underlying diseases including peptic ulcers, asthma, h...

background: systemic lupus erythematosus (sle) has various presentations in children. hematologic abnormalities is common in childhood onset of sle, however, isolated thrombocytopenia is relatively rare. thus, we present a child with isolated thrombocytopenia as a rare presentation of sle. case presentation: a 12-year-old boy with chief complaints of loss of appetite, weight loss, decreased pla...

a twelve year old girl, an established case of systemic lupus erythematosus, was referred to us suffering from diplopia and nasal speech for a period of 3 months. neurological examination was conducted which revealed a right-sided sixth nerve palsy and a pulsatile nasopharyngeal mass. neurodiagnostic imaging studies confirmed a giant intracavernous internal carotid aneurysm. the malady of the a...

introduction this study was conducted to evaluate the involvement of body organs such as the lungs in systemic lupus erythematosus (sle). little information exists on lung involvement in lupus patients without respiratory symptoms; we aimed to evaluate the characteristics of lung gas transfer in female sle patients using carbon monoxide diffusion capacity (dlco) in comparison with a control gro...

Background:Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement and periods of relapse and remission that mainly affects young women of childbearing age. In this regard the reproductive health is an important issue. Although diagnosis, treatment and management of pregnancy in SLE women have been improved recently, but the main concern is effects of SLE on ...

background: systemic lupus erythematous is an autoimmune disease associated with atherosclerotic manifestations or metabolic disturbance due to inflammation. the aim of this study was to determine frequency of metabolic syndrome (mets) in sle compared to healthy controls. methods: in this cross-sectional study, 150 sle patients and 220 healthy volunteers were enrolled. mets was diagnosed accord...

hemophagocytic syndrome (hps) is an uncommon manifestation in systemic lupus erythematosus (sle). clinical features of hps include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. hps comprises primary and reactive forms. herein, we describe a case of untreated sle with hps as one of the first manifestations of systemic lupus.

Lupus anticoagulant, concentrations of anticardiolipin antibodies, antithrombin III, plasminogen, (free) protein S, protein C, prothrombin, platelet counts, and bleeding times were determined in 74 lupus patients (58 with systemic lupus erythematosus; 16 with lupus-like disease) to establish the presence of risk factors for thrombosis in these patients. Of the variables evaluated, lupus anticoa...