نتایج جستجو برای: lymphocyte antiproliferative factor

تعداد نتایج: 904013  

Journal: :Molecular pharmacology 2007
Juan Román Alberto Fernández de Arriba Sonia Barrón Pedro Michelena Marta Giral Manuel Merlos Elvira Bailón Mònica Comalada Julio Gálvez Antonio Zarzuelo Isabel Ramis

2-Hydroxy-4(-2,2,3,3,3-pentafluoropropoxy)-benzoic acid (UR-1505), a new molecule chemically related to salicylic acid, has immunomodulator properties and is currently under clinical development for treatment of atopic dermatitis. The present work describes the immunomodulatory profile of UR-1505. UR-1505 targets T cells, inhibiting their proliferation and cytokine production by blocking nuclea...

E Baghizadeh, H Khara ,

The purpose of this study was to determine changes in hematological and plasma indices of Common Carp Cyprinus carpio with regard to age, sex and hormonal treatment. Sixty fish were used to assess the age factor. Also, 20 fish including female and male were assigned to determine blood indices with regard to sex and hormonal treatment. The pituitary gland extract was used as hormone for males an...

Journal: :Acta clinica Croatica 2010
Ana Ozura Alojz Ihan

Stress is the key psychological activator of the hypothalamic-pituitary-adrenal axis and therefore an important risk factor for diminished immunocompetence. The aim of the study was to assess the connection between the strategies of coping with stress and lymphocyte counts in soldiers. Coping strategies were evaluated in 61 Slovenian Army members using the Coping Responses Inventory. White bloo...

Journal: :Blood 2013
Wei Xu Tiffany Carr Kevin Ramirez Stephanie McGregor Mikael Sigvardsson Barbara L Kee

The E2A transcription factors promote the development of thymus-seeding cells, but it remains unknown whether these proteins play a role in T lymphocyte lineage specification or commitment. Here, we showed that E2A proteins were required to promote T-lymphocyte commitment from DN2 thymocytes and to extinguish their potential for alternative fates. E2A proteins functioned in DN2 cells to limit e...

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