نتایج جستجو برای: lymphotoxin
تعداد نتایج: 1222 فیلتر نتایج به سال:
Submit Manuscript | http://medcraveonline.com Abbreviations: AGE: Advanced Glycation End-Product; Angii: Angiotensin II; CAD: Coronary Artery Disease; Dia-1: Diaphanous-1; DN: Dominant-Negative; Hba1c: Glycated Haemoglobin; HMGB1: High-Mobility Group Box-1; LTA: Lymphotoxin Α; NF-Κb: Nuclear Factor Κb; NMD: Nonsense-Mediated Mrna-Decay; PBX2: Pre-BCell Leukaemia Homeobox 5; RAGE: Receptor for A...
Neoplastic cells are thought to have defective expression of costimulatory molecules. However, in this study, we show that human melanoma cells express LIGHT/TNFSF14, a ligand of herpesvirus entry mediator on T cells and of lymphotoxin B receptor on stromal cells. In vitro , melanoma cells stained for LIGHT in the intracellular compartment, with weak or negative cell surface expression. However...
A Th1 response is required for the development of Plasmodium berghei ANKA (PbA)-induced experimental cerebral malaria (ECM). The role of pro-Th1 IL-12 in malaria is complex and controversial. In this study, we addressed the role of IL-12Rβ2 in ECM development. C57BL/6 mice deficient for IL-12Rβ2, IL-12p40, or IL-12p35 were analyzed for ECM development after blood-stage PbA infection in terms of...
The critical role of tumor necrosis factor (TNF) as a mediator in autoimmune inflammatory processes is evident from in vivo studies with TNF-blocking agents. However, the mechanisms by which TNF, and possibly also its homologue lymphotoxin alpha, contributes to development of pathology in rheumatoid arthritis and Crohn disease and in animal models like experimental autoimmune encephalomyelitis ...
Abstract The characteristics of COVID-19 patients with persistent SARS-CoV-2 infection are not yet well described. Here, we compare the clinical and molecular features long duration viral shedding (LDs) those from short (SDs), healthy donors (HDs). We find that several cytokines chemokines, such as interleukin (IL)-2, tumor necrosis factor (TNF) lymphotoxin ? (LT-?) present at lower levels in L...
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