نتایج جستجو برای: m5 decision tree
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رشد سریع شهرها و روندصنعتی شدن ، مشکلات زیست محیطی زیادی را در بسیاری از شهرهای جهان ایجاد کرده است.آگاهی از روند تغییرات پوشش و کاربری اراضی طی دوره های زمانی طولانی برای برنامه ریزان و مدیران به منظور ارزیابی و پیش بینی مشکلات ناشی از این تغییرات بسیار با اهمیت است. سنجش از دور ابزار موثری برای پایش تغییرات پوشش اراضی درمناطق شهری و حوالی آن می باشد. شهر یاسوج در چند دهه اخیر بواسطه رشد و بدن...
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background: it is estimated that major depression disorders constitute 8.2% of years lived with disability (ylds) globally. the repetitive transcranial magnetic stimulation (rtms) and electroconvulsive therapy (ect) are two relative common interventions to treat major depressive disorders, especially for treatment resistant depression. in this study the cost- effectiveness and cost-utility of r...
the aim of this study was to estimate suspended sediment by the ann model, dt with cart algorithm and different types of src, in ten stations from the lorestan province of iran. the results showed that the accuracy of ann with levenberg-marquardt back propagation algorithm is more than the two other models, especially in high discharges. comparison of different intervals in models showed that r...
Of the five muscarinic receptor subtypes, the M5 receptor is the only one detectable in midbrain dopaminergic neurons, making it an attractive potential therapeutic target for treating disorders in which dopaminergic signaling is disrupted. However, developing an understanding of the role of M5 in regulating midbrain dopamine neuron function has been hampered by a lack of subtype-selective comp...
The available studies for estimating the characteristics of hydraulic jump are only for artificial or natural beds, and very limited researches have simultaneously considered artificial and natural beds. The aim of this study is to present comprehensive equations and models for predicting the characteristics of hydraulic jump in artificial and natural rough beds with various dimensions, arrange...
A functional high throughput screen identified a novel chemotype for the positive allosteric modulation (PAM) of the muscarinic acetylcholine receptor (mAChR) subtype 5 (M5). Application of rapid analog, iterative parallel synthesis efficiently optimized M5 potency to arrive at the most potent M5 PAMs prepared to date and provided tool compound 8n (ML380) demonstrating modest CNS penetration (h...
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